Microfluidics and Nanofluidics

, Volume 10, Issue 1, pp 29–35 | Cite as

Transport in two-dimensional paper networks

  • Elain Fu
  • Stephen A. Ramsey
  • Peter Kauffman
  • Barry Lutz
  • Paul Yager
Research Paper


Two-dimensional paper networks (2DPNs) hold great potential for transcending the capabilities and performance of today’s paper-based analytical devices. Specifically, 2DPNs enable sophisticated multi-step chemical processing sequences for sample pretreatment and analysis at a cost and ease-of-use that make them appropriate for use in settings with low resources. A quantitative understanding of flow in paper networks is essential to realize the potential of these networks. In this report, we provide a framework for understanding flow in simple 2DPNs using experiments, analytical expressions, and computational simulations.


Two-dimensional paper networks Paper microfluidics Fluid transport 



We thank Benedict Hui for assistance with the fabrication of 2DPNs. We gratefully acknowledge the support of NIH Grant No. 1RC1EB010593.

Supplementary material

10404_2010_643_MOESM1_ESM.docx (466 kb)
Supplementary material 1 (DOCX 464 kb)


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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Elain Fu
    • 1
  • Stephen A. Ramsey
    • 2
  • Peter Kauffman
    • 1
  • Barry Lutz
    • 1
  • Paul Yager
    • 1
  1. 1.Department of BioengineeringUniversity of WashingtonSeattleUSA
  2. 2.Institute for Systems BiologySeattleUSA

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