Lab-on-a-display: a new microparticle manipulation platform using a liquid crystal display (LCD)
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This paper reports a new portable microfluidic platform, “lab-on-a-display,” that microparticles are manipulated by optoelectronic tweezers (OET) on a liquid crystal display (LCD). The OET has been constructed by assembling a ground layer, a liquid chamber, and a photoconductive layer. Without lens or optical alignments, the LCD image directly forms virtual electrodes on the photoconductive layer for dielectrophoretic manipulation. The lab-on-a-display was first realized by a conventional monochromatic LCD module and a light source brighter than 5,000 lux. It was successfully applied to the programmable manipulation of 45 μm polystyrene beads; more than 100 particles were transported with an optical image-driven control, following the moving edge of the image at every moment. The effects of bead size and bias voltage on the manipulation speed were also investigated. Due to the portability and compatibility for disposable applications, this new platform has potential for programmable particle manipulation or chip-based bioprocessing including cell separation and bead-based analysis.
KeywordsMicrofluidics Lab-on-a-display Liquid crystal display (LCD) Optoelectronic tweezers Dielectrophoresis Particle manipulation
This research was supported by the Nano/Bio Science & Technology Program (M10536090002-05N3609-00210) of the Ministry of Science and Technology (MOST), Korea. The authors also thank CHUNG Moon Soul Center for BioInformation and BioElectronics, KAIST. The microfabrication works were performed at the Digital Nanolocomotion Center (KAIST, Daejeon, Korea) and the TFT-LCD Research Center (Kyung Hee University, Seoul, Korea).
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