Endoscopic ultrasonography for the evaluation of pancreatic cystic neoplasms

  • Eizaburo OhnoEmail author
  • Yoshiki Hirooka
  • Hiroki Kawashima
  • Takuya Ishikawa
  • Mitsuhiro Fujishiro
Special Feature: Review Article Ultrasonographic diagnosis of pancreatic diseases-This is all you need


Endoscopic ultrasonography (EUS) is a modality with high spatial resolution that enables comprehensive observation of the entire pancreas and plays an important role in the diagnosis of pancreatic lesions. Recent advances in diagnostic imaging methods such as ultrasound, computed tomography, and magnetic resonance imaging have increased the incidental detection of pancreatic cystic lesions (PCLs). EUS has been recognized as an essential diagnostic method for the detection and evaluation of PCLs. EUS has two important roles: as a detailed (high-resolution) imaging diagnostic method and as an approach for collecting cyst fluid content by EUS-guided fine needle aspiration for pathological diagnosis or biomarker evaluation. Furthermore, in recent years, the usefulness of contrast-enhanced EUS for the differential diagnosis of PCLs or evaluation of grade of malignancy, and a novel imaging technique called needle-based confocal laser endomicroscopy to observe intraductal structures through a needle, has been reported. An understanding of the morphological characteristics of PCLs depicted by ultrasound imaging and of the benefits and limitations of EUS diagnosis in daily practice is needed.


Endoscopic ultrasound Pancreatic cystic neoplasms Contrast-enhanced endoscopic ultrasound Endoscopic ultrasound-fine needle aspiration Intraductal papillary mucinous neoplasm 


Compliance with ethical standards

Conflict of interest

The authors declare no conflicts of interest for this article.

Ethical statement

As this is a review article based on published literature, no ethics approval was required.

Supplementary material

10396_2019_980_MOESM1_ESM.docx (17 kb)
Supplementary material 1 (DOCX 16 kb)


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Copyright information

© The Japan Society of Ultrasonics in Medicine 2019

Authors and Affiliations

  • Eizaburo Ohno
    • 1
    Email author
  • Yoshiki Hirooka
    • 2
  • Hiroki Kawashima
    • 1
  • Takuya Ishikawa
    • 1
  • Mitsuhiro Fujishiro
    • 1
  1. 1.Department of Gastroenterology and HepatologyNagoya University Graduate School of MedicineNagoyaJapan
  2. 2.Department of Liver, Biliary Tract and Pancreas DiseasesFujita Health UniversityAichiJapan

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