Shear wave velocity of the healthy thyroid gland in children with acoustic radiation force impulse elastography
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Abstract
Purpose
Acoustic radiation force impulse imaging is a kind of shear wave elastography that can be used in children for differentiating thyroid pathologies. Possible changes in the healthy thyroid gland in children may create difficulties in the use of shear wave velocities (SWV) in thyroid pathologies. The aim of this study was to define the normal values of SWV for the healthy thyroid gland in children, elucidate the correlation of the SWV values with potential influencing factors, and evaluate intra-operator reproducibility of the SWV.
Methods
Between January 2015 and December 2015, a total of 145 healthy children (81 girls, 64 boys; mean age, 10.5 ± 3.14 years; range 6–17 years) were enrolled in the study. The SWV and volume of the thyroid gland were determined.
Results
The mean shear wave velocity of the thyroid gland was 1.22 ± 0.20 m/s. There was no correlation between age and the mean SWV of the thyroid gland (Spearman Rho = 0.049, p = 0.556). There was also no correlation between the thyroid gland volume or BSA and the mean SWV. The only correlation detected was between BSA and total thyroid gland volume (p < 0.001).
Conclusion
In the present study, the SWV of the healthy thyroid gland in children was determined. There was no correlation between the SWV of the thyroid gland and age, BSA, or thyroid gland volume.
Keywords
Acoustic radiation force impulse elastography Children Thyroid gland UltrasonographyNotes
Compliance with ethical standards
Ethical statements
The present study was approved by the ethical committee of the hospital.
Conflict of interest
The authors declare that they have no conflicts of interest.
References
- 1.Youk JH, Son EJ, Park AY, et al. Shear-wave elastography for breast masses: local shear wave speed (m/s) versus Young modulus (kPa). Ultrasonography. 2014;33:34–9.CrossRefPubMedGoogle Scholar
- 2.Nightingale K. Acoustic radiation force impulse (ARFI) imaging: a review. Curr Med Imaging Rev. 2011;7:328.CrossRefPubMedPubMedCentralGoogle Scholar
- 3.Grazhdani H, Cantisani V, Lodise P, et al. Prospective evaluation of acoustic radiation force impulse technology in the differentiation of thyroid nodules: accuracy and interobserver variability assessment. J Ultrasound. 2014;17:13–20.CrossRefPubMedPubMedCentralGoogle Scholar
- 4.Zhang YF, He Y, Xu HX, et al. Virtual touch tissue imaging on acoustic radiation force impulse elastography a new technique for differential diagnosis between benign and malignant thyroid nodules. J Ultrasound Med. 2014;33:585–95.CrossRefPubMedGoogle Scholar
- 5.Zhang YF, Liu C, Xu HX, et al. Acoustic radiation force impulse imaging: a new tool for the diagnosis of papillary thyroid microcarcinoma. Biomed Res Int. 2014;2014:416969.Google Scholar
- 6.Zhang YF, Xu JM, Xu HX, et al. Acoustic radiation force impulse elastography: a useful tool for differential diagnosis of thyroid nodules and recommending fine-needle aspiration: a diagnostic accuracy study. Medicine (Baltimore). 2015;94(42):e1834.CrossRefGoogle Scholar
- 7.Kwak JY, Kim EK. Ultrasound elastography for thyroid nodules: recent advances. Ultrasonography. 2014;33:75.CrossRefPubMedPubMedCentralGoogle Scholar
- 8.Sporea I, Sirli R, Bota S, et al. ARFI elastography for the evaluation of diffuse thyroid gland pathology: preliminary results. World J Radiol. 2012;4:174.CrossRefPubMedPubMedCentralGoogle Scholar
- 9.Hamidi C, Göya C, Hattapoğlu S, et al. Acoustic radiation force impulse (ARFI) imaging for the distinction between benign and malignant thyroid nodules. Radiol Med (Torino). 2015;120:579–83.CrossRefGoogle Scholar
- 10.Nightingale K, Soo MS, Nightingale R, et al. Acoustic radiation force impulse imaging: in vivo demonstration of clinical feasibility. Ultrasound Med Biol. 2002;28:227–35.CrossRefPubMedGoogle Scholar
- 11.Liu BJ, Xu HX, Zhang YF, et al. Acoustic radiation force impulse elastography for differentiation of benign and malignant thyroid nodules with concurrent Hashimoto’s thyroiditis. Med Oncol. 2015;32:1–9.CrossRefGoogle Scholar
- 12.Rallison ML, Dobyns BM, Meikle AW, et al. Natural history of thyroid abnormalities: prevalence, incidence, and regression of thyroid diseases in adolescents and young adults. Am J Med. 1991;91:363–70.CrossRefPubMedGoogle Scholar
- 13.Corrias A, Mussa A, Baronio F, et al. Diagnostic features of thyroid nodules in pediatrics. Arch Pediatr Adolesc Med. 2010;164:714–9.CrossRefPubMedGoogle Scholar
- 14.Moon HJ, Sung JM, Kim EK, et al. Diagnostic performance of gray-scale US and elastography in solid thyroid nodules. Radiology. 2012;262:1002–13.CrossRefPubMedGoogle Scholar
- 15.Brown R. Autoimmune thyroiditis in childhood. 2013.Google Scholar
- 16.Hegedüs L. The thyroid nodule. N Engl J Med. 2004;351:1764–71.CrossRefPubMedGoogle Scholar
- 17.Niedziela M. Thyroid nodules. Best Pract Res Clin Endocrinol Metab. 2014;28:245–77.CrossRefPubMedGoogle Scholar
- 18.Friedrich-Rust M, Romenski O, Meyer G, et al. Acoustic radiation force impulse-imaging for the evaluation of the thyroid gland: a limited patient feasibility study. Ultrasonics. 2012;52:69–74.CrossRefPubMedGoogle Scholar
- 19.Brown RS. Disorders of the thyroid gland in infancy, childhood and adolescence. 2012.Google Scholar
- 20.Zurakowski D, Di Canzio J, Majzoub JA. Pediatric reference intervals for serum thyroxine, triiodothyronine, thyrotropin, and free thyroxine. Clin Chem. 1999;45:1087–91.PubMedGoogle Scholar
- 21.Arda K, Ciledag N, Aktas E, et al. Quantitative assessment of normal soft-tissue elasticity using shear-wave ultrasound elastography. Am J Roentgenol. 2011;197:532–6.CrossRefGoogle Scholar
- 22.Vlad M, Golu I, Bota S, et al. Real-time shear wave elastography may predict autoimmune thyroid disease. Wien Klin Wochenschr. 2015;127:330–6.CrossRefPubMedGoogle Scholar
- 23.Sebag F, Vaillant-Lombard J, Berbis J, et al. Shear wave elastography: a new ultrasound imaging mode for the differential diagnosis of benign and malignant thyroid nodules. J Clin Endocrinol Metab. 2010;95:5281–8.CrossRefPubMedGoogle Scholar