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Journal of Medical Ultrasonics

, Volume 44, Issue 2, pp 183–190 | Cite as

Measurement of carotid pulse wave velocity using ultrafast ultrasound imaging in hypertensive patients

  • Xiaopeng Li
  • Jue Jiang
  • Hong Zhang
  • Hua Wang
  • Donggang Han
  • Qi ZhouEmail author
  • Ya Gao
  • Shanshan Yu
  • Yanhua Qi
Original Article

Abstract

Purpose

The study aimed to assess the utility of ultrafast ultrasound imaging for evaluation of carotid pulse wave velocity (PWV) in newly diagnosed hypertension patients.

Methods

This prospective non-randomized study enrolled 90 hypertensive patients in our hospital from September to December 2013 as a hypertension group. An age- and sex-matched cohort of 50 healthy adults in our hospital from September to December 2013 was also included in the study as a control group. Carotid PWV at the beginning and at the end of systole (PWV-BS and PWV-ES, respectively) and intima-media thickness (IMT) were measured by ultrafast ultrasound imaging technology. The associations of PWV-BS, PWV-ES, and IMT with hypertension stage were evaluated by Spearman correlation analysis.

Results

PWV-BS and PWV-ES in the hypertension group were significantly elevated compared with those in control group. Different hypertension stages significantly differed in PWV-BS and PWV-ES. PWV-BS and PWV-ES appeared to increase with the hypertension stage. Moreover, IMT, PWV-BS, and PWV-ES were positively correlated with the hypertension stage in hypertensive patients.

Conclusion

Ultrafast ultrasound imaging was a valid and convenient method for the measurement of carotid PWV in hypertensive patients. Ultrafast ultrasound imaging might be recommended as a promising alternative method for early detection of arterial abnormality in clinical practice.

Keywords

Ultrafast ultrasound imaging Essential hypertension Carotid artery elasticity Carotid pulse wave velocity 

Notes

Compliance with ethical standards

Conflict of interest

None.

Ethical statements

The study was approved by the medical ethics committee of the Second Affiliated Hospital of Xi’an Jiaotong University, and written informed consent was received from each participant.

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Copyright information

© The Japan Society of Ultrasonics in Medicine 2016

Authors and Affiliations

  • Xiaopeng Li
    • 1
  • Jue Jiang
    • 1
  • Hong Zhang
    • 1
  • Hua Wang
    • 1
  • Donggang Han
    • 1
  • Qi Zhou
    • 1
    Email author
  • Ya Gao
    • 1
  • Shanshan Yu
    • 1
  • Yanhua Qi
    • 1
  1. 1.Department of Ultrasound, The Second Affiliated HospitalMedical School of Xi’an Jiaotong UniversityXi’anChina

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