EcoHealth

, Volume 2, Issue 4, pp 291–306

Beyond Disciplinary Boundaries: Leptospirosis as a Model of Incorporating Transdisciplinary Approaches to Understand Infectious Disease Emergence

  • Joseph M. Vinetz
  • Bruce A. Wilcox
  • Alonso Aguirre
  • Lisa X. Gollin
  • Alan R. Katz
  • Roger S. Fujioka
  • Kepa Maly
  • Pierre Horwitz
  • Healani Chang
Original Contributions

Abstract

Leptospirosis is a zoonotic infectious disease of global significance. Political, economic, demographic, ecologic, and other anthropogenically driven environmental changes have fueled the reemergence of this disease in industrialized and developing countries, and in both urban and rural settings. We argue that conventional disciplinary, even interdisciplinary, research methods are not sufficient to elucidate the complex mechanisms and causal relationships among the myriad factors responsible for infectious disease emergence. To address the significant gaps in the field of leptospirosis, an integrated research agenda is needed to guide successful public health remediation of the disease. Based on both working group analysis of literature and newly obtained information, we describe cross-disciplinary collaborative approaches that allow a novel approach to understand leptospirosis emergence with regard to mountain-to-sea ecosystems in Hawai‘i and other region-specific ecosystems. Leptospirosis research is a model for how complementary disciplines in the social, cultural, ecological, and biomedical sciences can optimally interact towards a higher understanding of emerging infectious diseases.

Keywords

ecology environmental health zoonotic diseases anthropogenic change cultural health models indigenous knowledge 

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Copyright information

© EcoHealth Journal Consortium 2005

Authors and Affiliations

  • Joseph M. Vinetz
    • 1
  • Bruce A. Wilcox
    • 2
  • Alonso Aguirre
    • 3
  • Lisa X. Gollin
    • 2
  • Alan R. Katz
    • 4
  • Roger S. Fujioka
    • 5
  • Kepa Maly
    • 2
  • Pierre Horwitz
    • 6
  • Healani Chang
    • 2
    • 7
  1. 1.Division of Infectious Diseases, Department of MedicineUniversity of California, San Diego School of MedicineLa Jolla
  2. 2.Division of Ecology and Health, Department of Tropical MedicineMedical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of HawaiiHonolulu
  3. 3.Wildlife TrustNew York
  4. 4.Department of Public Health Sciences and Epidemiology, John A. Burns School of MedicineUniversity of HawaiiHonolulu
  5. 5.Water Resources Research CenterUniversity of Hawaii at ManoaHonolulu
  6. 6.Consortium for Health and Ecology ProgramEdith Cowan UniversityJoondaloopAustralia
  7. 7.Pacific Biosciences Research CenterUniversity of HawaiiHonolulu

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