Reproducibility and reliability of retinal and optic disc measurements obtained with swept-source optical coherence tomography in a healthy population
To analyze the reproducibility of macular and peripapillary thickness measurements, and optic nerve morphometric data obtained with Triton Optical coherence tomography (OCT) in a healthy population.
Observational cross sectional study.
Material and methods
A total of 108 eyes underwent evaluation using the Triton Swept Source-OCT. A wide protocol was used and measurements in each eye were repeated three times. Morphometric data of the optic nerve head, full macular thickness, ganglion cell layer (GCL) and retinal nerve fiber layer thickness (RNFL) were analyzed. For each parameter, the coefficient of variation (COV) and the intra-class (ICC) correlation values were calculated.
Measurements were highly reproducible for all morphometric measurements of the optic disc, with a mean COV of 6.36%. Macular full thickness showed good COV and ICC coefficients, with a mean COV value of 1.00%. Macular GCL thickness showed a mean COV value of 3.06%, and ICC higher than 0.787. Peripapillary RNFL thickness showed good COV and ICC coefficients, with a mean COV value of 8.31% and ICC higher than 0.684. The inferotemporal sector showed the lowest ICC (0.685).
Triton OCT presents good reproducibility values in measurements corresponding to retinal parameters, with macular measurements showing the highest reproducibility rates. Peripapillary RNFL measurements should be evaluated with caution.
KeywordsCoefficient of variation Reproducibility Swept source Optical coherence tomography
Conflicts of interest
M. Satue, None; A. Gavin, None; E. Orduna, None; E. Vilades, None; M. J. Rodrigo, None; J. Obis, None; V. Polo, None; J. M. Larrosa, None; L. E. Pablo, None; E. G. -Martin, None.
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