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Japanese Journal of Ophthalmology

, Volume 56, Issue 3, pp 273–279 | Cite as

Corneal displacement during tonometry with a noncontact tonometer

  • Yoshiaki KiuchiEmail author
  • Makoto Kaneko
  • Hideki Mochizuki
  • Joji Takenaka
  • Kenji Yamada
  • Junko Tanaka
Laboratory Investigation

Abstract

Purpose

To measure the extent of corneal displacement during the early phase of tonometry using a noncontact tonometer and to determine the factors that affect the extent of the displacement.

Methods

The cornea was photographed in profile by use of a high-speed camera during tonometry with a noncontact tonometer. The frame rate of the camera was 5,000 frames/s. The extent of the displacement of the central corneal area at 13.2 ms after application of the air puff was measured in 115 healthy volunteers. The factors that affected the extent of the corneal displacement were determined by stepwise multiple linear regression analysis.

Results

The subjects’ age, sex, intraocular pressure (IOP), central corneal thickness, anterior chamber depth, and axial length were selected by the stepwise method. The results of the multiple linear regression analysis showed that subjects with low IOP, of older age, and of male sex had significantly greater displacement of the central cornea.

Conclusions

High-speed photography can be used to evaluate the degree of corneal displacement during tonometry with a noncontact tonometer. The amount of corneal displacement is affected by the individual’s IOP, age, and sex.

Keywords

Noncontact tonometer High-speed camera Corneal displacement Ocular bioproperty 

Notes

Acknowledgment

This work was partially supported by grant no. 22591965 from the Japanese Ministry of Education, Culture, Science and Technology.

References

  1. 1.
    American Academy of Ophthalmology Glaucoma Panel. Preferred practice pattern guidelines. Primary open-angle glaucoma. San Francisco: American Academy of Ophthalmology; 2010. http://www.aao.org/ppp.
  2. 2.
    Herndon LW, Choudhri SA, Cox T, Damji KF, Shields MB, Allingham RR. Central corneal thickness in normal, glaucomatous, and ocular hypertensive eyes. Arch Ophthalmol. 1997;115:1137–41.PubMedCrossRefGoogle Scholar
  3. 3.
    Paranhos A Jr, Paranhos FR, Prata JA, Omi CA, Mello PA, Shields MB. Influence of keratometric readings on comparative intraocular pressure measurements with Goldmann, Tono-Pen, and noncontact tonometers. J Glaucoma. 2000;9:219–23.PubMedCrossRefGoogle Scholar
  4. 4.
    Doughty MJ, Zaman ML. Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach. Surv Ophthalmol. 2000;44:367–408.PubMedCrossRefGoogle Scholar
  5. 5.
    Damji KF, Muni RH, Munger RM. Influence of corneal variables on accuracy of intraocular pressure measurement. J Glaucoma. 2003;12:69–80.PubMedCrossRefGoogle Scholar
  6. 6.
    Emara B, Probst LE, Tingey DP, Kennedy DW, Willms LJ, Machat J. Correlation of intraocular pressure and central corneal thickness in normal myopic eyes and after laser in situ keratomileusis. J Cataract Refract Surg. 1998;24:1320–5.PubMedGoogle Scholar
  7. 7.
    Friedenwald JS. Contribution to the theory and practice of tonometry. Am J Ophthalmol. 1937;20:985–1024.Google Scholar
  8. 8.
    Pallikaris IG, Kymionis GD, Ginis HS, Kounis GA, Tsilimbaris MK. Ocular rigidity in living human eyes. Invest Ophthalmol Vis Sci. 2005;46:409–14.PubMedCrossRefGoogle Scholar
  9. 9.
    Elsheikh A, Wang D, Pye D. Determination of the modulus of elasticity of the human cornea. J Refract Surg. 2007;23:808–18.PubMedGoogle Scholar
  10. 10.
    Knox Cartwright NE, Tyrer JR, Marshall J. Age-related differences in the elasticity of the human cornea. Invest Ophthalmol Vis Sci. 2011;52:4324–9.PubMedCrossRefGoogle Scholar
  11. 11.
    Kempf R, Kurita Y, Iida Y, Kaneko M, Mishima H, Tsukamoto H, et al. Dynamic properties of human eyes. Conf Proc IEEE Eng Med Biol Soc. 2005;3:3180–3.PubMedGoogle Scholar
  12. 12.
    Kempf R, Kurita Y, Iida Y, Kaneko M, Sugimoto E, Tsukamoto H, et al. Understanding eye deformation in non-contact tonometry. Conf Proc IEEE Eng Med Biol Soc. 2006;1:5428–31.PubMedCrossRefGoogle Scholar
  13. 13.
    Newsome DA, Foidart JM, Hassell JR, Krachmer JH, Rodrigues MM, Katz SI. Detection of specific collagen types in normal and keratoconus corneas. Invest Ophthalmol Vis Sci. 1981;20:738–50.PubMedGoogle Scholar
  14. 14.
    Ricard-Blum S, Ville G. Collagen cross-linking. Int J Biochem. 1989;21:1185–9.PubMedCrossRefGoogle Scholar
  15. 15.
    Richards SC, Olson RJ, Brodstein DE, Richards WL. Differences between men and women as related to intraocular lens implantation. Ophthalmic Surg. 1986;17:82–7.PubMedGoogle Scholar
  16. 16.
    Goto T, Klyce SD, Zheng X, Maeda N, Kuroda T, Ide C. Gender- and age-related differences in corneal topography. Cornea. 2001;20:270–6.PubMedCrossRefGoogle Scholar
  17. 17.
    Weinreb RN, Lu A, Beeson C. Maternal corneal thickness during pregnancy. Am J Ophthalmol. 1988;105:258–60.PubMedGoogle Scholar
  18. 18.
    Wickham LA, Rocha EM, Gao J, Krenzer KL, da Silveira LA, Toda I, et al. Identification and hormonal control of sex steroid receptors in the eye. Adv Exp Med Biol. 1998;438:95–100.PubMedCrossRefGoogle Scholar
  19. 19.
    Luce DA. Determining in vivo biomechanical properties of the cornea with an ocular response analyzer. J Cataract Refract Surg. 2005;31:156–62.PubMedCrossRefGoogle Scholar
  20. 20.
    Kotecha A, Elsheikh A, Roberts CR, Zhu H, Garway-Heath DF. Corneal thickness- and age-related biomechanical properties of the cornea measured with the ocular response analyzer. Invest Ophthalmol Vis Sci. 2006;47:5337–47.PubMedCrossRefGoogle Scholar
  21. 21.
    Allingham RR. Shields’ textbook of glaucoma. 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. p. 36–58.Google Scholar

Copyright information

© Japanese Ophthalmological Society 2012

Authors and Affiliations

  • Yoshiaki Kiuchi
    • 1
    Email author
  • Makoto Kaneko
    • 2
  • Hideki Mochizuki
    • 1
  • Joji Takenaka
    • 1
  • Kenji Yamada
    • 2
  • Junko Tanaka
    • 3
  1. 1.Department of Ophthalmology and Visual ScienceGraduate School of Biomedical Sciences, Hiroshima UniversityHiroshimaJapan
  2. 2.Department of Mechanical EngineeringGraduate School of Engineering, Osaka UniversityOsakaJapan
  3. 3.Department of Epidemiology, Infectious Disease Control and PreventionGraduate School of Biomedical Science, Hiroshima UniversityHiroshimaJapan

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