Japanese Journal of Ophthalmology

, Volume 53, Issue 5, pp 486–489 | Cite as

Prophylactic vitrectomy for acute retinal necrosis

  • Tomoka Ishida
  • Yoshiharu SugamotoEmail author
  • Sunao Sugita
  • Manabu Mochizuki
Clinical Investigation



To evaluate the efficacy of prophylactic vitrectomy for acute retinal necrosis.


The clinical charts of 17 patients (18 eyes) with acute retinal necrosis and no retinal break or rhegmatogenous retinal detachment (RRD) were retrospectively analyzed for the efficacy of prophylactic vitrectomy. The retinal necrotic lesions at the initial presentation were classified into three groups according to the lesion site as described by Holland: zone 1 (posterior pole; n = 3), zone 2 (midperiphery; n = 12), and zone 3 (periphery; n = 3). All patients were treated with intravenous antiviral therapy. Three zone 1 eyes and eight zone 2 eyes underwent prophylactic vitrectomy. Four zone 2 eyes and three zone 3 eyes did not receive prophylactic vitrectomy.


All zone 1 eyes developed RRD despite prophylactic vitrectomy. Among the 12 zone 2 eyes, eight of the eyes that underwent prophylactic vitrectomy did not develop RRD, whereas three of the four zone 2 eyes without prophylactic vitrectomy developed RRD. All zone 3 eyes were cured with only antiviral medication.


Prophylactic vitrectomy is effective in preventing the development of RRD in eyes where necrotic lesions do not extend beyond the midperiphery (zone 2).


acute retinal necrosis prophylactic vitrectomy rhegmatogenous retinal detachment 


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Copyright information

© Japanese Ophthalmological Society (JOS) 2009

Authors and Affiliations

  • Tomoka Ishida
    • 1
    • 2
  • Yoshiharu Sugamoto
    • 2
    • 3
    Email author
  • Sunao Sugita
    • 2
  • Manabu Mochizuki
    • 2
  1. 1.Department of Ophthalmology, Tokyo Metropolitan Cancer and Infectious Disease CenterKomagome HospitalTokyoJapan
  2. 2.Department of Ophthalmology and Visual Science, Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityTokyoJapan
  3. 3.Department of Ophthalmology and Visual Science, Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityTokyoJapan

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