An Asian Patient with Intraocular Lymphoma Treated by Intravitreal Methotrexate
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To demonstrate the efficacy of intravitreal methotrexate for treating intraocular lymphoma.
A 55-year-old immunocompetent Asian man was diagnosed with intraocular lymphoma.
The patient was initially managed by intravenous administration of high-dose methotrexate. Because vitreous cells persisted after systemic chemotherapy, methotrexate was given intravitreally thereafter. There was only self-limited corneal epitheliopathy without major complications following intraocular injections. Ocular remission was sustained during a 21-month follow-up.
Intravitreal methotrexate is an effective, repeatable, and safe treatment for intraocular lymphoma. Jpn J Ophthalmol 2006;50:474–478 © Japanese Ophthalmological Society 2006
Key wordschemotherapy intraocular lymphoma intravitreal injection methotrexate primary central nervous system lymphoma
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