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Japanese Journal of Ophthalmology

, Volume 48, Issue 6, pp 587–590 | Cite as

Comparison of 0.1% Bromfenac Sodium and 0.1% Pemirolast Potassium for the Treatment of Allergic Conjunctivitis

  • Minori Miyake-Kashima
  • Yoji Takano
  • Mari Tanaka
  • Yoshiyuki Satake
  • Tetsuya Kawakita
  • Murat Dogru
  • Naoko Asano-Kato
  • Kazumi Fukagawa
  • Hiroshi Fujishima
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Abstract

Purpose

We compared the efficacy of a new nonsteroidal antiinflammatory drug (NSAID) eye drop, 0.1% bromfenac sodium (Bromfenac), with that of an antiallergic agent, 0.1% pemirolast potassium (Pemirolast), in the treatment of seasonal allergic conjunctivitis in Japanese patients.

Methods

Twenty-two subjects with seasonal allergic conjunctivitis were enrolled in the study. One eye was treated with Bromfenac eye drops and the contralateral eye was treated with Pemirolast eye drops for 1 week. Subjective ocular symptoms and objective ocular signs evaluated by slit-lamp examination were scored and recorded before and after treatment.

Results

Both drugs significantly decreased ocular signs after 1 week, but not symptoms. No significant differences in subjective symptoms or objective signs were observed between the two drugs. Ten patients (45.5%) selected Bromfenac as more effective, nine patients (40.9%) selected Pemirolast, and three patients found no difference in efficacy between the two drugs.

Conclusion

Bromfenac sodium is as safe and effective for the treatment of allergic conjunctivitis as pemirolast potassium. Jpn J Ophthalmol 2004;48:587–590 © Japanese Ophthalmological Society 2004

Key words

allergic conjunctivitis nonsteroidal antiinflammatory drug objective ocular signs subjective ocular symptoms 

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Copyright information

© Japanese Ophthalmological Society 2004

Authors and Affiliations

  • Minori Miyake-Kashima
    • 1
  • Yoji Takano
    • 1
  • Mari Tanaka
    • 1
  • Yoshiyuki Satake
    • 1
  • Tetsuya Kawakita
    • 1
  • Murat Dogru
    • 2
  • Naoko Asano-Kato
    • 1
  • Kazumi Fukagawa
    • 2
  • Hiroshi Fujishima
    • 2
  1. 1.Department of OphthalmologyTokyo Dental CollegeChibaJapan
  2. 2.Department of OphthalmologyKeio University School of MedicineTokyoJapan

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