Japanese Journal of Ophthalmology

, Volume 48, Issue 4, pp 386–391 | Cite as

Clinical Features and Prognosis in Ocular Toxoplasmosis

  • Leyla S. Atmaca
  • Tülay Simsek
  • Figen Batioglu
Clinical Investigation



To evaluate retrospectively the clinical characteristics, complications, and prognosis in patients with ocular toxoplasmosis.

Patients and Methods

We reviewed the records of 189 patients (243 eyes) with ocular toxoplasmosis who were examined between 1972 and 1999. Color fundus photography and, in some patients, fluorescein angiography and indocyanine green angiography were performed. There were 98 male (52%) and 91 female (48%) patients with a mean age of 22.8 ± 8.9 years.


Of the patients, 140 (74%) had congenital and 49 (26%) had acquired toxoplasmosis. At the initial examination, there were active lesions in 65 eyes and inactive lesions in 178 eyes. Active lesions included retinochoroiditis in 59 (91%), papillitis in 2 (3%), and neuroretinitis in 4 (6%) eyes. There was also an inactive scar in 17 eyes with active retinochoroiditis. Localisation of the active retinochoroiditis was the macula in 44 (74%), the macula and peripheral retina in 3 (5%), the peripheral retina in 9 (15%) and the peripapillary retina in 3 (5%) eyes. Optic atrophy, pigment epithelial detachment, choroidal neovascularization, lamellar macular hole, and retinal neovascularization were seen during the follow-up period.


Ocular toxoplasmosis commonly affects the macula and seriously impairs visual acuity. The prevention of acquired and congenital infections is very important in controlling ocular toxoplasmosis. Patients should be followed to avoid late complications.

Key words

acquired toxoplasmosis congenital toxoplasmosis ocular toxoplasmosis toxoplasmic retinochoroiditis 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Japanese Ophthalmological Society 2004

Authors and Affiliations

  • Leyla S. Atmaca
    • 1
  • Tülay Simsek
    • 2
  • Figen Batioglu
    • 1
  1. 1.Department of OphthalmologyAnkara University Faculty of MedicineAnkaraTurkey
  2. 2.Ankara Social Security Eye HospitalAnkaraTurkey

Personalised recommendations