Wiener Medizinische Wochenschrift

, Volume 159, Issue 13–14, pp 355–358 | Cite as

Intracardiac metastasis of a Malignant Mixed Mullerian Tumor (MMMT): Progressive dyspnoea due to obstruction of the left atrium and the left ventricle without left ventricular dysfunction or primary lung disease

  • Ludger J. Ulbricht
  • Matthias Kunert
  • Bernhard Gremmler
  • Nikolaos Evagelopoulos
  • Arno Krian
  • Jürgen Moege
Fallbericht

Summary

Malignant Mixed Mullerian tumors (MMMT) are rare gynecological tumors. Even with surgical treatment, chemotherapy, and/or radiotherapy, outcome is poor. MMMTs are known to metastasize to the liver, the abdomen, and the lungs. One case of an ocular metastasis has been reported. In a 61-year-old female patient who had undergone surgical resection of a Mullerian tumor of the uterus 26 months prior to being admitted to our department, we found an obstructing left atrial mass. Histopathologic assessment of this lesion after surgical resection revealed a Mullerian tumor metastasis. Immediately after surgery, the patient was asymptomatic, but was readmitted 4 months later with dyspnoea. Echocardiography and CT revealed new masses in the left atrium and left ventricle. On a literature review, we did not find any description of left atrial and left ventricular occluding metastases of MMMT.

Keywords

Malignant Mixed Mullerian tumor (MMMT) Carcinosarcoma Palliative surgery Intracavitary cardiac metastases 

Intrakardiale Metastase eines malignen Müllerschen Mischtumors (MMMT): Progressive Luftnot aufgrund einer Obstruktion des linken Vorhofs und des linken Ventrikels ohne linksventrikuläre Funktionseinschränkung oder primäre Lungenerkrankung

Zusammenfassung

Maligne Müllersche Mischtumore (MMMT) sind seltene gynäkologische Tumore. Auch mittels chirurgischer Therapie, Chemotherapie und/oder Strahlentherapie sind die Ergebnisse mäßig. Bekannte Metastasierungswege sind die Leber, das Abdomen und die Lunge. Einmal wurde von einer okkulären Metastase berichtet. Hier wird der Fall einer 61-jährigen Patientin demonstriert, bei der wir eine linksatriale Tumormasse 26 Monate nach Operation eines MMMT nachweisen konnten. Die Histopathologie nach chirurgischer Resektion des Tumors wies eine Metastase des Müllerschen Mischtumors auf. Postoperativ war die Patientin asymptomatisch. 4 Monate später waren dann jedoch wiederum metastatische diesmal den gesamten linken Vorhof und linken Ventrikel ausmauernde Massen zu diagnostizieren. Eine erneute operative Intervention war nicht möglich.

Schlüsselwörter

Maligner Müllerscher Mischtumor (MMMT) Karzinosarkome Palliative Chirurgie Intrakavitäre kardiale Metastasen 

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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Ludger J. Ulbricht
    • 1
    • 2
  • Matthias Kunert
    • 1
  • Bernhard Gremmler
    • 1
  • Nikolaos Evagelopoulos
    • 3
  • Arno Krian
    • 3
  • Jürgen Moege
    • 4
  1. 1.Department of CardiologyMarienhospital BottropBottropGermany
  2. 2.University of Witten/HerdeckeWittenGermany
  3. 3.Department of Cardiovascular SurgeryDuisburg Heart CenterDuisburgGermany
  4. 4.Pathology PracticeMarienhospital BottropBottropGermany

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