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Chromatographia

, Volume 80, Issue 3, pp 437–446 | Cite as

HPLC Determination of Hexythiazox in Food Samples by MISPE Extraction

  • Javad Feizy
  • Azizollah NezhadaliEmail author
  • Zarrin Es’haghi
  • Hamed Reza Beheshti
Original

Abstract

A new molecularly imprinted polymer (MIP) was prepared for trace analysis of hexythiazox (HTZ) in food samples. In this research, HTZ was used as a template molecule. The MIP was synthesized using pyrrole as a functional monomer. The parameters that affect the efficiency of the method were thoroughly investigated. These parameters were desorption solvent, amount of sorbent, pH and ionic strength. The measurements were done under the optimal conditions. The limit of detection and limit of quantification of method were 71 and 236 ng g−1, respectively. The relative standard deviation (RSD %) of standard solutions of 1000 and 2000 µg L−1 were 0.08 and 0.51%, respectively. The linear range was determined as 100–2000 µg L−1. Application of the method was examined to separation and preconcentration of HTZ in some food samples, with success.

Graphical Abstract

Keywords

HPLC Solid phase extraction Molecularly imprinted polymer Hexythiazox 

Notes

Compliance with ethical standards

Conflict of interest

All authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Javad Feizy
    • 1
  • Azizollah Nezhadali
    • 2
    • 3
    Email author
  • Zarrin Es’haghi
    • 2
    • 3
  • Hamed Reza Beheshti
    • 4
  1. 1.Research Institute of Food Science and TechnologyMashhadIran
  2. 2.Department of ChemistryPayame Noor UniversityMashhadIran
  3. 3.Department of ChemistryPayame Noor UniversityTehranIran
  4. 4.Testa Quality Control LaboratoryNorth-East Food Industrial Technology and Biotechnology ParkMashhadIran

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