Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI
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Integrated whole-body PET/MRI tomographs have become available. PET/MR imaging has the potential to supplement, or even replace combined PET/CT imaging in selected clinical indications. However, this is true only if methodological pitfalls and image artifacts arising from novel MR-based attenuation correction (MR-AC) are fully understood.
Here we present PET/MR image artifacts following routine MR-AC, as most frequently observed in clinical operations of an integrated whole-body PET/MRI system.
A clinical adoption of integrated PET/MRI should entail the joint image display and interpretation of MR data, MR-based attenuation maps and uncorrected plus attenuation-corrected PET images in order to recognize potential pitfalls from MR-AC and to ensure clinically accurate image interpretation.
KeywordsPET/MRI MR-based attenuation correction Image artifacts Pitfalls
- 1.Wernick MN, Aarsvold JN (2004) Emission tomography. The Fundamentals of SPECT and PET. Academic Press, ISBN: 978-0127 444 826Google Scholar
- 2.Bailey DL, Townsend DW, Valk PE and Maisey MN (2005) Positron emission tomography: basic science and clinical practice. Springer, London, ISBN: 978-1852 334 857Google Scholar
- 12.Kalemis A, Delattre BM, Heinzer S (2012) Sequential whole-body PET/MR scanner—concept, clinical use and optimisations after two years in the clinic. The manufacturer’s perspective. Magn Reson Mater Phy (Epub ahead of print Aug 7)Google Scholar
- 17.Sattler B, Jochimsen T, Barthel H et al (2012) Physical and organizational provision for installation, regulatory requirements and implementation of a simultaneous hybrid PET/MR-imaging system in an integrated research and clinical setting. Magn Reson Mater Phy (paper included in this issue)Google Scholar
- 18.Keereman V, Mollet P, Berker Y, Schulz V, Vandenberghe S et al (2012) Challenges and current methods for attenuation correction in PET-MR. Magn Reson Mater Phy (paper included in this issue)Google Scholar
- 25.Larsson A et al (2012) Evaluation of an attenuation correction method for brain PET/MRI based on substitute CT-imag. Magn Reson Mater Phy (paper included in this issue)Google Scholar