MR venography of the human brain using susceptibility weighted imaging at very high field strength

  • Peter J. Koopmans
  • Rashindra Manniesing
  • Wiro J. Niessen
  • Max A. Viergever
  • Markus Barth
Research Article



We investigate the implications of high magnetic field strength on MR venography based on susceptibility-weighted imaging (SWI) and estimate the optimum echo time to obtain maximum contrast between blood and brain tissue.

Materials and methods

We measured tissue contrast and T2* relaxation times at 7 T of gray matter, white matter, and venous blood in vivo.


T2* relaxation times of gray matter, white matter, and venous blood in vivo yielded 32.9 ± 2.3, 27.7 ± 4.3, and 7.4 ± 1.4 ms, respectively. Optimum TE was found to be 15 ms which is supported by theoretical considerations. Using this optimum TE, we acquired 3D high resolution datasets with a large volume coverage in a short measurement time that show very detailed microanatomical structures of the human brain such as intracortical veins and laminar cortical substructures.


By applying optimised vessel filters (vesselness filter and vessel enhancing diffusion) whole brain MR venograms can be obtained at 7 T with a significantly reduced measurement time compared to 3 T.


Neuroimaging Venography 3 T 7 T Parallel imaging Vessel segmentation Vessel enhancing diffusion Transverse relaxation times 


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Copyright information

© ESMRMB 2008

Authors and Affiliations

  • Peter J. Koopmans
    • 1
  • Rashindra Manniesing
    • 2
  • Wiro J. Niessen
    • 2
  • Max A. Viergever
    • 3
  • Markus Barth
    • 1
    • 4
  1. 1.F.C. Donders Centre for Cognitive NeuroimagingRadboud University NijmegenNijmegenThe Netherlands
  2. 2.Department of Medical Informatics and RadiologyRotterdamThe Netherlands
  3. 3.Image Sciences InstituteUniversity Medical CenterUtrechtThe Netherlands
  4. 4.Erwin L. Hahn Institute for Magnetic Resonance ImagingUniversity Duisburg-EssenEssenGermany

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