MRI of the lung using hyperpolarized 3He at very low magnetic field (3 mT)

  • C.P. Bidinosti
  • J. Choukeife
  • G. Tastevin
  • P.-J. Nacher
  • A. Vignaud
Article

DOI: 10.1007/s10334-004-0035-y

Cite this article as:
Bidinosti, C., Choukeife, J., Tastevin, G. et al. MAGMA (2004) 16: 255. doi:10.1007/s10334-004-0035-y

Abstract

Optical pumping of 3He produces large (hyper) nuclear-spin polarizations independent of the magnetic resonance imaging (MRI) field strength. This allows lung MRI to be performed at reduced fields with many associated benefits, such as lower tissue susceptibility gradients and decreased power absorption rates. Here we present results of 2D imaging as well as accurate 1D gas diffusion mapping of the human lung using 3He at very low field (3 mT). Furthermore, measurements of transverse relaxation in zero applied gradient are shown to accurately track pulmonary O2 partial pressure, opening the way for novel imaging sequences.

Keywords

Hyperpolarized helium Relaxation Lung MRI Oxygen Very low field 

Copyright information

© ESMRMB 2004

Authors and Affiliations

  • C.P. Bidinosti
    • 1
  • J. Choukeife
    • 2
  • G. Tastevin
    • 2
  • P.-J. Nacher
    • 2
  • A. Vignaud
    • 3
  1. 1.Department of PhysicsSimon Fraser UniversityBurnabyCanada
  2. 2.Laboratoire Kastler BrosselParisFrance
  3. 3.U2R2MUniversité Paris SudOrsay CedexFrance

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