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Hilar cholangiocarcinoma with synchronous metastases to breast and skeletal muscle: A case report and literature review

  • Ding Guanghui 
  • Yang Jiahe 
  • Cheng Shuqun 
  • Gong Hua 
  • Liu Kai 
  • Dai Binghua 
  • Gong Biao 
  • Zhao Lihua 
  • Cong Wenming 
  • Wu Mengchao 
Article

Abstract

Hilar cholangiocarcinoma has been reputed as a slow growth tumor in the past. Skeletal muscle is one of the most unusual sites of metastasis from any malignancy. We report herein a case of hilar cholangiocarcinoma with synchronous metastases to skeletal muscle and breast, and review the literature. The patient was a 48-year-old woman who presented with jaundice and weight loss. An inoperable hilar cholangiocarcinoma was diagnosed. She was treated with a combination of endoscopic plastic stent biliary drainage and three-dimensional conformal radiotherapy (3DCRT). Good response was achieved. Ten months later, she exhibited with a painful metastatic mass in the muscle rectus femoris of left thigh and a painless mass in the left breast. She underwent operation to relieve the pain, but died from liver failure after 8 months. The literature only offers isolated cases of cholangiocarcinoma with distant metastases, of which the common sites were cervical lymph node, bone, and portal venous system. Most patients were presented with multiple metastases with extensive local disease.

Key words

hilar cholangiocarcinoma distant metastasis endoscopic stent three-dimensional conformal radiotherapy palliative treatment 

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Copyright information

© Editorial Office of the Chinese-German Journal of Clinical Oncology 2006

Authors and Affiliations

  • Ding Guanghui 
    • 1
  • Yang Jiahe 
    • 1
  • Cheng Shuqun 
    • 1
  • Gong Hua 
    • 1
  • Liu Kai 
    • 1
  • Dai Binghua 
    • 1
  • Gong Biao 
    • 2
  • Zhao Lihua 
    • 3
  • Cong Wenming 
    • 4
  • Wu Mengchao 
    • 1
  1. 1.Department of Comprehensive Treatment, Eastern Hepatobiliary Surgery HospitalSecond Military Medical UniversityShanghaiChina
  2. 2.Department of Endoscopy, Eastern Hepatobiliary Surgery HospitalSecond Military Medical UniversityShanghaiChina
  3. 3.Department of Radiation Oncology, Eastern Hepatobiliary Surgery HospitalSecond Military Medical UniversityShanghaiChina
  4. 4.Department of Pathology, Eastern Hepatobiliary Surgery HospitalSecond Military Medical UniversityShanghaiChina

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