Zeitschrift für Epileptologie

, Volume 22, Issue 2, pp 80–88 | Cite as

Invasive Hirnstimulationsverfahren in der Epilepsietherapie

Originalarbeit

Zusammenfassung

Epilepsiepatienten, denen weder pharmakologische noch epilepsiechirurgische Therapien helfen oder angeboten werden können, stehen wenige ergänzende therapeutische Verfahren zu Verfügung. Methoden der Hirnstimulation wie die Vagusnervstimulation (VNS) oder die Tiefenhirnstimulation („deep brain stimulation“, DBS) gehören dazu. Angesichts der ungünstigen Prognosen therapierefraktärer oder katastrophaler Epilepsien sind diese Verfahren Gegenstand vielfältiger Forschungsbemühungen. Der folgende Beitrag soll eine Einleitung in Erkenntnisse und Perspektiven invasiver Stimulationsverfahren unter Berücksichtigung der gegenwärtigen klinischen Praxis geben.

Schlüsselwörter

Epilepsie Stimulation Vagusnervstimulation „Deep brain stimulation“ Thalamus 

Invasive stimulation techniques in epilepsy therapy

Abstract

For patients with epilepsy not responding or not being eligible for pharmacological treatment or epilepsy surgery, therapeutic options are limited. Alternative therapeutic options include methods of brain stimulation like vagus nerve stimulation (VNS) or deep brain stimulation (DBS). In recent years, these methods have been subject of considerable research efforts given the unfavorable prognosis of refractory or catastrophic epilepsies. The following review provides a basic introduction into clinical praxis, current knowledge and prospects of invasive stimulation techniques.

Keywords

Epilepsy Stimulation Vagus nerve stimulation Deep brain stimulation Thalamus 

Notes

Interessenkonflikt

Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

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Copyright information

© Springer 2009

Authors and Affiliations

  1. 1.Abteilung für Klinische NeurophysiologieUniversitätsklinikum GöttingenGöttingenDeutschland
  2. 2.Department of NeurologyCase Western Reserve UniversityClevelandUSA

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