Phytothérapie

, Volume 5, Issue 4, pp 194–203 | Cite as

L’utilisation des plantes médicinales dans le traitement du diabète au Maroc

  • M. Eddouks
  • M. L. Ouahidi
  • O. Farid
  • A. Moufid
  • A. Khalidi
  • A. Lemhadri
Article Original Pharmacognosie

Résumé

Le traitement actuel du diabète est efficace dans la baisse de la glycémie, cependant le contrôle adéquat quotidien de la glycémie est très difficile à atteindre dans la plupart des cas, ce qui conduit à long terme à l’émergence de complications très sérieuses. L’essor récent de la phytothérapie offre une opportunité pour trouver des molécules naturelles susceptibles d’exercer des effets bénéfiques sur la régulation du métabolisme glucidique en évitant les effets secondaires des substances synthétiques. Le Maroc, riche par sa biodiversité et son climat, est une plate-forme géographique très importante qui mérite d’être explorée dans le domaine de la recherche de molécules hypoglycémiantes originaires de plantes qui ont pour longtemps servi à une grande tranche de population comme moyen incontournable de médication. L’objectif de ce travail est de présenter des données actuelles sur l’utilisation des plantes médicinales dans le traitement du diabète au Maroc.

Mots clés

Diabète Phytothérapie Plantes hypoglycémiantes Maroc 

The use of medicinal plants in the treatment of diabetes in Morocco

Abstract

The current treatment of diabetes is efficacious as far as the decrease of glycaemia is concerned, however, effective control of glycaemia is difficult to achieve in many cases and leads to the emergence of serious long term complications. Phytotherapy offers a valuable opportunity to discover new natural molecules with beneficial effects on glucose homeostasis and without any of the side effects currently observed in modern therapy. Morocco, with its rich biodiversity and climate represents an important geographical field for exploration with regard to hypoglycaemic molecules found in plants that had for a long time represented a source of medication for a large proportion of the population. The objective of this study is to present current data on the use of hypoglycaemic plants for treating diabetes mellitus in Morocco.

Keywords

Diabetes Phytotherapy Hypoglycaemic plants Morocco 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Bibliographie

  1. 1.
    Atta-Ur-Rahman, Zaman K (1989) Medicinal plants with hypoglycemic activity. J Ethnopharmacol 26: 1–55PubMedCrossRefGoogle Scholar
  2. 2.
    Bailey CJ, Day C (1989) Traditional plant medicines as treatment for diabetes. Diabetes Care 12: 553–64PubMedCrossRefGoogle Scholar
  3. 3.
    Bellakhdar J, Claisse R, Fleurentin J, Younos C (1991) Repertory of standard herbal drugs in the Moroccan pharmacopoeia. J Ethnopharmacol 35: 123–43PubMedCrossRefGoogle Scholar
  4. 4.
    Bellakhdar J (1997) La pharmacopée marocaine traditionnelle: Médecine arabe ancienne et savoirs populaires. Éditions Ibis Press, ParisGoogle Scholar
  5. 5.
    De Smet PA (2002) Herbal remedies. N Engl J Med 347(25): 2046–57PubMedCrossRefGoogle Scholar
  6. 6.
    Eddouks M (2006) Aspects of food medicine and ethnopharmacology in Morocco. In: Eating and healing: traditional food and medicine. Eds Haworth press, New York, pp. 357–82Google Scholar
  7. 7.
    Eddouks M, Maghrani M, Lemhadri A, et al. (2002) Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the southeast region of Morocco (Tafilalet). J Ethnopharmacol 82(2–3): 97–103PubMedCrossRefGoogle Scholar
  8. 8.
    El-Hilaly J, Hmammouchi M, Lyoussi B (2003) Ethnobotanical studies and economic evaluation of medicinal plants in Taounate provine (Northern Morocco). J Ethnopharmacol 86: 149–58PubMedCrossRefGoogle Scholar
  9. 9.
    Ernst E (1997) Plants with hypoglycaemic activity in humains. Phytomedicine 4(1): 73–8Google Scholar
  10. 10.
    Eisenberg DM, Kessler RC, Foster C, et al. (1993) Unconventional medicine in the United States. N Engl J Med 328: 246–52PubMedCrossRefGoogle Scholar
  11. 11.
    Fabricant DS, Farnsworth NR (2001) The value of plants used in traditional medicine for drug discovery. Environ Health Perspect 109: 69–75PubMedCrossRefGoogle Scholar
  12. 12.
    Farnsworth NR, Akerele O, Bingel AS, et al. (1985) Medicinal plants in therapy. Bull World Health Organ 63: 965–81PubMedGoogle Scholar
  13. 13.
    Grover JK, Yadav S, Vats V (2002) Medicinal plants of India with anti-diabetic potentiel. J Ethnopharmacol 81: 81–100PubMedCrossRefGoogle Scholar
  14. 14.
    Heinrich M (2000) Ethnobotany and its role in drug development. Phytother Res 14: 479–88PubMedCrossRefGoogle Scholar
  15. 15.
    Hmammouchi M (1999) Les plantes médicinales et aromatiques marocaines. Édition Imprimeries de Fedala, Rabat, MarocGoogle Scholar
  16. 16.
    Ivorra MD, Paya M, Villar A (1989) A review of natural products and plants as potentiel antidiabetic drugs. J Ethnopharmacol 27: 243–75PubMedCrossRefGoogle Scholar
  17. 17.
    Jaouhari JT (2002) Contribution à l’étude phytochimique, pharmacologique et clinique d’une plante réputée hypoglycémiante: Zygophyllum gaetulum EMB. et Maire. Thèse de doctorat d’État. Université Cady Ayyad, Faculté des sciences Semlalia, MarrakechGoogle Scholar
  18. 18.
    Jouad H, Haloui M, Rhiouani H, et al. (2001) Ethnobotanical survey of medicinal plants used for the treatment of diabetes, cardiac and renal diseases in the North centre region of Morocco (Fez-Boulemane). J Ethnopharmacol 77(2–3): 175–82PubMedCrossRefGoogle Scholar
  19. 19.
    Kahouaji MS (1995) Contribution à une étude ethnobotanique des plantes médicinales au Maroc oriental. Thèse de diplôme d’études supérieures de 3e cycle. Université Mohamed Ier, Faculté des sciences, OujdaGoogle Scholar
  20. 20.
    King H, Aubert R, Herman WH (1998) Global burden of diabetes, 1995–2025. Diabetes Care 21: 1414–31PubMedCrossRefGoogle Scholar
  21. 21.
    Merzouki A, Ed-Derfouri F, Morelo-Mesa J (2000) Contribution to the knowledge of Rifian traditional medicine. II: Folk medicine in Ksar Lkbir district (NW Morocco). Fitoterapia 71: 278–307PubMedCrossRefGoogle Scholar
  22. 22.
    Merzouki A, Ed-derfouri F, Morelo-Mesa J (2003) Contribution to the knowledge of Rifian traditional medicine. III: Phytotherapy of diabetes in Chefchaouen province (North of Morocco). Ars Pharmaceutica 44(1): 59–67Google Scholar
  23. 23.
    Marles RJ, Farnsworth NR (1995) Antidiabetic plants and their active constituents. Phytomedicine 2: 13–189Google Scholar
  24. 24.
    Oubré AY, Carlson TJ, King SR, et al (1997) From plant to patient: an ethnomedical approach to the identification of news drugs for the treatment of NIDDM. Diabetologia 40: 614–7PubMedCrossRefGoogle Scholar
  25. 25.
    Rates SMK (2001) Plants as source of drugs. Toxicon 39: 603–13PubMedCrossRefGoogle Scholar
  26. 26.
    Sijelmassi A (1993) Les plantes médicinales du Maroc. Édition le Fennec, Casablanca, MarocGoogle Scholar
  27. 27.
    Srivastava AK, Mehdi MZ (2005) Insulino-mimetic and anti-diabetic effects of vanadium compounds. Diabet Med 22(1): 2–13PubMedCrossRefGoogle Scholar
  28. 28.
    Tazi AM, Abir-Khalil S, Chaouki N, et al. (2003) Prevalence of the main cardiovascular risk factors in Morocco: results of a National Survey, 2000. J Hypertens 21: 897–903PubMedCrossRefGoogle Scholar
  29. 29.
    The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (2002) Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 25(suppl. 1): S5–S15Google Scholar
  30. 30.
    Wang HX, Ng TB (1999) Natural products with hypoglycemic, hypotensive, hypocholesterolimic, antiatherosclerotic and anti-thrombotic activities. Life Sci 65(25): 2663–77PubMedCrossRefGoogle Scholar
  31. 31.
    WHO (2002) Fact Sheet No. 271. Word Health Organisation, GenevaGoogle Scholar
  32. 32.
    Yaniv Z, Dafni A, Friedman J, Palevitch D (1987) Plants used for the treatment of diabetes in Israel. J Ethnopharmacol 2: 145–51CrossRefGoogle Scholar
  33. 33.
    Ziyyat A, Legssyer H, Mekhfi A, et al. (1997) Phytotherapy of hypertension and diabetes in Oriental Morocco. J Ethnopharmacol 58: 45–54PubMedCrossRefGoogle Scholar

Copyright information

© Springer Verlag 2007

Authors and Affiliations

  • M. Eddouks
    • 1
  • M. L. Ouahidi
    • 1
  • O. Farid
    • 1
  • A. Moufid
    • 1
  • A. Khalidi
    • 1
  • A. Lemhadri
    • 1
  1. 1.Physiologie et pharmacologie endocrinienneFaculté des sciences et techniques ErrachidiaBoutalamine, ErrachidiaMaroc

Personalised recommendations