Journal of Industrial Microbiology & Biotechnology

, Volume 37, Issue 10, pp 1033–1040

Development of succinic acid production from corncob hydrolysate by Actinobacillus succinogenes

Original Paper

DOI: 10.1007/s10295-010-0750-5

Cite this article as:
Yu, J., Li, Z., Ye, Q. et al. J Ind Microbiol Biotechnol (2010) 37: 1033. doi:10.1007/s10295-010-0750-5


Succinic acid is one of the most important platform chemicals since it has great potential in industrial applications. In this study, corncob hydrolysate was used for succinic acid production. After diluted acid treatment, xylose was released from hemicellulose as the predominant monosaccharide in the hydrolysate, whereas glucose was released very little and most was retained as cellulose in the raw material. Without any detoxification, corncob hydrolysate was used directly as the carbon source in the fermentation. Actinobacillus succinogenes could utilize the sugars in the hydrolysate to produce succinic acid efficiently. Through medium optimization, yeast extract was selected as the nitrogen source and MgCO3 was used to control pH. A total of 23.64 g/l of succinic acid was produced with a yield of 0.58 g/g based on consumed sugar, indicating that the waste corncob residue can be used to produce value-added chemicals practically.


Actinobacillus succinogenes Succinic acid Corncob hydrolysate Xylose Optimization 

Copyright information

© Society for Industrial Microbiology 2010

Authors and Affiliations

  • Jie Yu
    • 1
    • 2
  • Zhimin Li
    • 1
  • Qin Ye
    • 1
  • Yong Yang
    • 2
  • Shulin Chen
    • 2
  1. 1.State Key Laboratory of Bioreactor EngineeringEast China University of Science and TechnologyShanghaiChina
  2. 2.Institute of MicrobiologyChinese Academy of SciencesBeijingChina

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