Clinical Autonomic Research

, Volume 21, Issue 1, pp 65–67

Tako-tsubo cardiomyopathy in a patient with bilateral lesions in the dorsal medulla

  • Koldo Berganzo
  • Roberto Ciordia
  • Juan C. Gómez-Esteban
  • Beatriz Tijero
  • Marta Agundez
  • Fernando Velasco
  • Maria A. Valle
  • Juan J. Zarranz
Case Report

Abstract

Tako-tsubo-like cardiomyopathy (TTC) is much more common than originally thought. The exact pathophysiology of TTC is unclear. The most accepted theory proposes myocardial stunning of neurogenic origin, supported by the frequent antecedent of emotional or physical stress, suggesting a catecholamine-mediated mechanism. We present a patient with this syndrome and bilateral damage of the dorsal medulla oblongata likely affecting both solitary tract nuclei. Our case points to a link between baroreflex failure and TTC, highlighting the important role of sympathetic discharge in the pathophysiology of TTC.

Keywords

Tako-tsubo cardiomyopathy Solitary tract nucleus Baroreflex failure 

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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Koldo Berganzo
    • 1
    • 2
  • Roberto Ciordia
    • 1
    • 2
  • Juan C. Gómez-Esteban
    • 1
    • 2
  • Beatriz Tijero
    • 1
    • 2
  • Marta Agundez
    • 1
    • 2
  • Fernando Velasco
    • 1
    • 2
  • Maria A. Valle
    • 1
    • 2
  • Juan J. Zarranz
    • 1
    • 2
  1. 1.Department of NeurologyHospital CrucesBaracaldo, VizcayaSpain
  2. 2.Department of NeurosciencesUniversity of the Basque Country (UPV/EHU)BilbaoSpain

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