Clinical Autonomic Research

, Volume 18, Supplement 1, pp 14–18

Current pharmacologic treatment for orthostatic hypotension



Orthostatic hypotension is treated effectively with the combined use of non-pharmacological and pharmacological interventions. Patients should be counseled as to the nature of the underlying disorder and reversible causes of orthostatic hypotension should be removed. Should symptoms persist, pharmacological treatment is implemented. First line pharmacotherapeutic interventions include volume repletion in combination with alpha-adrenoreceptor agonists. If unsuccessful there are several supplementary agents with different mechanisms of action that may provide an additive effect.

Key words

orthostatic hypotension syncope autonomic failure sympathetic nervous system 

Copyright information

© Springer 2008

Authors and Affiliations

  1. 1.Dept. of Neurology Harvard Medical SchoolCenter for Autonomic and Peripheral Nerve Disorders Beth Israel Deaconess Medical CenterBostonUSA

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