Clinical Autonomic Research

, Volume 17, Issue 3, pp 193–196 | Cite as

Heart rate variability and autonomic function tests in HIV positive individuals in India

  • Ankit Sakhuja
  • Ankur Goyal
  • Ashok Kumar Jaryal
  • Naveet Wig
  • Madhu Vajpayee
  • Ajay Kumar
  • Kishore Kumar Deepak
RESEARCH LETTER
First Online:
Received:
Accepted:

Abstract

Supine heart rate variability (HRV) and autonomic tests were carried to determine whether autonomic activity was affected in HIV positive patients. The pressor response following handgrip and cold pressor test was blunted in HIV+ patients, and the degree of dysfunction correlated with CD4 cell counts. The extent of autonomic impairment was mild and subclinical.

Keywords

autonomic nervous system HIV symptoms sympathetic parasympathetic heart rate blood pressure 
This is a preview of subscription content, log in to check access.

References

  1. 1.
    Becker K, Gorlach I, Frieling T, Haussinger D (1997) Characterization and natural course of cardiac autonomic nervous dysfunction in HIV-infected patients. AIDS 11(6):751–757PubMedCrossRefGoogle Scholar
  2. 2.
    Craddock C, Pasvol G, Bull R, Protheroe A, Hopkin J (1987) Cardiorespiratory arrest and autonomic neuropathy in AIDS. Lancet 2(8549):16–18PubMedCrossRefGoogle Scholar
  3. 3.
    Heart rate variability standards of measurement, physiologic interpretation and clinical use (Task Force of the European Society of Cardiology and North American Society of Pacing and Electrophysiology) (1996) Circulation 93:1043–1065Google Scholar
  4. 4.
    Hohnloser SH, Klnigenheben T (1998) Basic autonomic tests. In: Malik M (ed). Clinical guide to cardiac autonomic tests. Kluwer Academic Publishers, London, 51–66Google Scholar
  5. 5.
    Miller RF, Semple SJ (1987) Autonomic neuropathy in AIDS. Lancet Aug 8;2(8554):343–344CrossRefGoogle Scholar
  6. 6.
    Mittal CM, Wig N, Mishra S, Deepak KK (2004) Heart rate variability in human immunodeficiency virus-positive individuals. Int J Cardiol 94(1):1–6PubMedCrossRefGoogle Scholar
  7. 7.
    National AIDS Control Organization (NACO), http://www.nacoonline.org/publication/7.pdf
  8. 8.
    Neild PJ, Amadi A, Ponikowski P, Coats AJ, Gazzard BG (2000) Cardiac autonomic dysfunction in AIDS is not secondary to heart failure. Int J Cardiol 74(2–3):133–137PubMedCrossRefGoogle Scholar
  9. 9.
    Parisi A, Perri GD, Maurizio S, Minoli L (1987) Testing for neurological involvement in HIV infection. Lancet 2(8574):1531–1532CrossRefGoogle Scholar
  10. 10.
    Ruttimann S, Hilti P, Spinas GA, Dubach UC (1991) High frequency of human immunodeficiency virus-associated autonomic neuropathy and more severe involvement in advanced stages of human immunodeficiency virus disease. Arch Intern Med 151(12):2441–2443PubMedCrossRefGoogle Scholar
  11. 11.
    Shahmanesh M, Bradbeer CS, Edwards A, Smith SE (1991) Autonomic dysfunction in patients with human immunodeficiency virus infection. Int J STD AIDS 2(6):419–423PubMedGoogle Scholar
  12. 12.
    Villa A, Foresti V, Confalonieri F. (1987) Autonomic neuropathy and HIV infection. Lancet 17;2(8564):915CrossRefGoogle Scholar
  13. 13.
    Welby SB, Rogerson SJ, Beeching NJ. (1991) Autonomic neuropathy is common in human immunodeficiency virus infection. J Infect 23(2):123–128PubMedCrossRefGoogle Scholar

Copyright information

© Springer 2007

Authors and Affiliations

  • Ankit Sakhuja
    • 1
  • Ankur Goyal
    • 1
  • Ashok Kumar Jaryal
    • 2
  • Naveet Wig
    • 1
  • Madhu Vajpayee
    • 3
  • Ajay Kumar
    • 1
  • Kishore Kumar Deepak
    • 2
  1. 1.Dept. of MedicineAll India Institute of Medical SciencesNew DelhiIndia
  2. 2.Dept. of PhysiologyAll India Institute of Medical SciencesNew DelhiIndia
  3. 3.Dept. of MicrobiologyAll India Institute of Medical SciencesNew DelhiIndia

Personalised recommendations