Clinical Autonomic Research

, 16:61 | Cite as

The effects of exercise training on myocardial adrenergic and muscarinic receptors

  • Julie Barbier*
  • Sylvia Reland*
  • Nathalie Ville
  • Françoise Rannou-Bekono
  • Sara Wong
  • François Carré


We investigated the effects of exercise training on heart rate variability (HRV) and myocardial adrenergic and muscarinic receptors in rats. Exercise training induced a decrease in body mass while ventricular size remained unchanged, a development we considered as a relative cardiac hypertrophy. In addition, there was a reduction in the density of myocardial β1-adrenergic receptors. These structural changes were associated with functional adaptations, as illustrated by the increased response of the sinus node to sympathetic blockade.

Key words

heart rate variability myocardial receptors physiological cardiac hypertrophy exercise training 


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Copyright information

© Steinkopff-Verlag 2006

Authors and Affiliations

  • Julie Barbier*
    • 1
    • 2
  • Sylvia Reland*
    • 2
    • 3
  • Nathalie Ville
    • 1
    • 2
    • 3
  • Françoise Rannou-Bekono
    • 1
    • 2
  • Sara Wong
    • 4
  • François Carré
    • 2
    • 3
  1. 1.Laboratory of Physiology and Biomechanics of Muscular ExerciseUFR-APS, University of Rennes 2Rennes CedexFrance
  2. 2.G. I. S. “Sciences of Movement”Rennes cedexFrance
  3. 3.EA 3194—Cardiovascular Research Group, Laboratory of Medical Physiology, Faculty of MedicineUniversity Rennes 1Rennes
  4. 4.Signal and Imagery Processing LaboratoryINSERM U 642, University Rennes 1RennesFrance

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