Clinical Autonomic Research

, Volume 14, Issue 3, pp 167–175

Use of lower abdominal compression to combat orthostatic hypotension in patients with autonomic dysfunction

  • Adrianus A. J. Smit
  • Wouter Wieling
  • Jiro Fujimura
  • Jong C. Denq
  • Tonette L. Opfer-Gehrking
  • Mohammed Akarriou
  • John M. Karemaker
  • Phillip A. Low
RESEARCH ARTICLE

DOI: 10.1007/s10286-004-0187-x

Cite this article as:
Smit, A.A.J., Wieling, W., Fujimura, J. et al. Clin Auton Res (2004) 14: 167. doi:10.1007/s10286-004-0187-x

Abstract.

The aim of this study was to investigate in patients with neurogenic orthostatic hypotension the mechanism and usefulness of abdominal compression to increase standing blood pressure. In three protocols, 23 patients underwent abdominal compression. Protocol 1 evaluated in a 40–60° head-up-tilt position, the effect of abdominal compression on caval vein and femoral diameter, arterial blood pressure and hemodynamics. Protocol 2 documented the relationship between the level of compression and the arterial pressure response. Protocol 3 investigated the ability to maintain standing blood pressure by an elastic binder. During head-up-tilt, compression (40 mm Hg) resulted in a reduction in diameter of the caval vein (mean –2.6mm, range –1.4 to 0.6), without a change in femoral vein diameter. Stroke volume increased by 14 % (range –1 to 23) and blood pressure (systolic/diastolic) by 30/14 mmHg (range 7/2 to 69/36), both p < 0.05; 40 mmHg compression was associated with a higher pressure response than 20 mmHg (mean 18/8 mmHg, range 6/2 to 43/20 vs. mean 9/4 mmHg, range –1/0 to 18/8, p < 0.05). Elastic abdominal binding increased standing blood pressure with 15/6mmHg (range –3/3 to 36/14, p < 0.05). We conclude that in patients with neurogenic orthostatic hypotension, abdominal compression increases standing blood pressure to a varying degree by increasing stroke volume.

Key words

autonomic nervous system blood pressure autonomic dysfunction braces abdominal compression 

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Copyright information

© Steinkopff Verlag 2004

Authors and Affiliations

  • Adrianus A. J. Smit
    • 1
  • Wouter Wieling
    • 1
  • Jiro Fujimura
    • 2
  • Jong C. Denq
    • 2
  • Tonette L. Opfer-Gehrking
    • 2
  • Mohammed Akarriou
    • 1
  • John M. Karemaker
    • 3
  • Phillip A. Low
    • 2
  1. 1.Dept. of Internal Medicine, Academic Medical CenterUniversity of AmsterdamAZ AmsterdamThe Netherlands
  2. 2.Mayo Clinic and Foundation Autonomic Reflex Laboratory, Dept. of Neurology Rochester (MN)USA
  3. 3.Dept. of Physiology, Academic Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands

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