Clinical Autonomic Research

, Volume 13, Issue 4, pp 256– 270 | Cite as

Sympathetic skin response

Basic mechanisms and clinical applications
  • R. VetrugnoMD
  • R. LiguoriMD
  • P. CortelliMD
  • P. MontagnaMD
REVIEW ARTICLE

Abstract.

Sympathetic skin response (SSR), defined as the momentary change of the electrical potential of the skin, may be spontaneous or reflexively evoked by a variety of internal or by externally applied arousal stimuli. Although the suprasegmental structures influencing the SSR in humans are not well known, SSR has been proposed as a non-invasive approach to investigate the function of the sympathetic system. SSR is easy to apply but current procedures are not sufficiently reliable for diagnostic purposes, and show imperfect correlations both with clinical features and other measurements of autonomic, in particular, sudomotor dysfunction.

Key words

sympathetic skin response autonomic system sweating sudomotor response neurophysiology 

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Copyright information

© Steinkopff Verlag 2003

Authors and Affiliations

  • R. VetrugnoMD
    • 1
    • 3
  • R. LiguoriMD
    • 1
  • P. CortelliMD
    • 2
  • P. MontagnaMD
    • 1
  1. 1.Dept. of Neurological SciencesUniversity of BolognaBolognaItaly
  2. 2.Institute of Clinical NeurologyUniversity of Modena and Reggio EmiliaModenaItaly
  3. 3.Dipartimento di Scienze Neurologichedell’Università di BolognaBolognaItaly

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