Journal of Digital Imaging

, Volume 20, Issue 1, pp 88–97 | Cite as

White Matter Fiber Tracking Computation Based on Diffusion Tensor Imaging for Clinical Applications

  • Paulo R. Dellani
  • Martin Glaser
  • Paulo R. Wille
  • Goran Vucurevic
  • Axel Stadie
  • Thomas Bauermann
  • Andrei Tropine
  • Axel Perneczky
  • Aldo von Wangenheim
  • Peter Stoeter
Article

Fiber tracking allows the in vivo reconstruction of human brain white matter fiber trajectories based on magnetic resonance diffusion tensor imaging (MR-DTI), but its application in the clinical routine is still in its infancy. In this study, we present a new software for fiber tracking, developed on top of a general-purpose DICOM (digital imaging and communications in medicine) framework, which can be easily integrated into existing picture archiving and communication system (PACS) of radiological institutions. Images combining anatomical information and the localization of different fiber tract trajectories can be encoded and exported in DICOM and Analyze formats, which are valuable resources in the clinical applications of this method. Fiber tracking was implemented based on existing line propagation algorithms, but it includes a heuristic for fiber crossings in the case of disk-shaped diffusion tensors. We successfully performed fiber tracking on MR-DTI data sets from 26 patients with different types of brain lesions affecting the corticospinal tracts. In all cases, the trajectories of the central spinal tract (pyramidal tract) were reconstructed and could be applied at the planning phase of the surgery as well as in intraoperative neuronavigation.

Key words

Diffusion tensor imaging fiber tracking pyramidal tract cortico-spinal tracts neurosurgical planning and navigation DICOM 

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Copyright information

© SCAR (Society for Computer Applications in Radiology) 2007

Authors and Affiliations

  • Paulo R. Dellani
    • 1
    • 3
  • Martin Glaser
    • 1
    • 2
  • Paulo R. Wille
    • 1
  • Goran Vucurevic
    • 1
  • Axel Stadie
    • 2
  • Thomas Bauermann
    • 1
  • Andrei Tropine
    • 1
  • Axel Perneczky
    • 2
  • Aldo von Wangenheim
    • 3
  • Peter Stoeter
    • 1
  1. 1.Institute of NeuroradiologyJohannes Gutenberg-University of MainzMainzGermany
  2. 2.Department of NeurosurgeryJohannes Gutenberg-University of MainzMainzGermany
  3. 3.Department of Statistics and Computer SciencesFederal University of Santa CatarinaSanta CatarinaBrazil

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