Journal of Plant Research

, Volume 116, Issue 3, pp 233–239 | Cite as

Biosynthesis of cytokinins

JPR Symposium


Cytokinins are adenine derivatives with an isoprenoid side chain and play an essential role in plant development. Plant isopentenyltransferases that catalyze the first and rate-limiting steps of cytokinin biosynthesis have recently been identified. Unlike bacterial enzymes, which catalyze the transfer of the isopentenyl moiety from dimethylallyldiphosphate (DMAPP) to the N6 position of adenosine 5′-monophosphate (AMP), plant enzymes catalyze the transfer of the isopentenyl moiety from DMAPP preferentially to ATP and to ADP. The isopentenylated side chain is hydroxylated to form zeatin-type cytokinins. An alternative pathway, in which a hydroxylated side chain is directly added to the N6 position of the adenine moiety, has also been suggested.


Arabidopsis AtIPTs Cytokinins DMAPP:ATP/ADP isopentenyltransferase Plant hormone 



I thank Thomas Moritz and Goran Sandberg for allowing me to cite unpublished data.


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Copyright information

© The Botanical Society of Japan and Springer-Verlag  2003

Authors and Affiliations

  1. 1.Department of Biology, Graduate School of ScienceOsaka UniversityToyonakaJapan
  2. 2.Precursory Research for Embryonic Science and Technology (PRESTO)Science and Technology CorporationKawaguchiJapan

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