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Clinical and Experimental Medicine

, Volume 12, Issue 3, pp 201–205 | Cite as

Malignant tumor-like gastric lesion due to candida albicans in a diabetic patient treated with cyclosporin: a case report and review of the literature

  • Pasquale MansuetoEmail author
  • Giuseppe Pisciotta
  • Giovanni Tomasello
  • Daniela Cabibi
  • Aurelio Seidita
  • Alberto D’Alcamo
  • Angelo Maria Patti
  • Delia Sprini
  • Antonio Carroccio
  • Giovam Battista Rini
  • Gaetana Di Fede
Case Report

Abstract

The gastrointestinal tract of healthy individuals is colonized by hundreds of saprophytes and mycetes, especially the Candida species, are habitual ones. Under certain conditions, the fungal flora may overgrow, resulting in lesions of the digestive mucosa which, rarely, can have a local diffusion and/or spread to the lympho-hematogenous system. Mycotic infections of the stomach can sometimes look like benign gastric ulcers. Here, we present the case report of a woman, aged 64, who presented with type II diabetes mellitus and psoriasis, on chronic treatment with cyclosporin A and with endoscopic evidence of an ulcerated, vegetating gastric lesion secondary to Candida albicans infection. Although strongly suggestive of malignancy, it completely healed after cyclosporin withdrawal and the administration of oral antifungal drugs.

Keywords

Candidiasis Mycotic infection of the gastrointestinal tract Submucosal tumor 

Notes

Conflict of interest

None.

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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Pasquale Mansueto
    • 1
    Email author
  • Giuseppe Pisciotta
    • 1
  • Giovanni Tomasello
    • 2
  • Daniela Cabibi
    • 3
  • Aurelio Seidita
    • 1
  • Alberto D’Alcamo
    • 1
  • Angelo Maria Patti
    • 1
  • Delia Sprini
    • 1
  • Antonio Carroccio
    • 4
  • Giovam Battista Rini
    • 1
  • Gaetana Di Fede
    • 1
  1. 1.Internal Medicine, Department of Clinical Medicine and Emerging DiseasesUniversity Hospital of PalermoPalermoItaly
  2. 2.Surgery DepartmentUniversity Hospital of PalermoPalermoItaly
  3. 3.Pathology DepartmentUniversity Hospital of PalermoPalermoItaly
  4. 4.Internal Medicine, Ospedali Civili Riuniti di Sciacca (AG)University of PalermoPalermoItaly

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