Clinical and Experimental Medicine

, Volume 8, Issue 2, pp 61–64 | Cite as

Myasthenia gravis and the thymus gland. A historical review

  • Marius Raica
  • Anca Maria Cimpean
  • Domenico RibattiEmail author


The first report of an association between myasthenia gravis (MG) and the thymus gland was in 1901. Although the underlying mechanisms are uncertain, thymic abnormalities are clearly associated with MG. This review article summarises, from a historical point of view, our knowledge of these associations, and the surgical and medical treatment of MG, including symptom management, immunosuppression, intravenous immunoglobulin and plasmapheresis.


History of medicine Myasthenia gravis Thymus gland 


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Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  • Marius Raica
    • 1
  • Anca Maria Cimpean
    • 1
  • Domenico Ribatti
    • 2
    Email author
  1. 1.Department of Histology and Cytology “Victor Babes”University of Medicine and PharmacyTimisoaraRomania
  2. 2.Department of Human Anatomy and HistologyUniversity of Bari Medical SchoolBariItaly

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