, Volume 19, Issue 1, pp 1–5 | Cite as

Lower sensitivity of cyprinid fishes to three acetylcholinesterase inhibitor pesticides: an evaluation based on no-effect concentrations

  • Yuichi Iwasaki
  • Marko Jusup
  • Kenichi Shibata
  • Takashi Nagai
  • Shosaku Kashiwada
Rapid communication Note on important and novel findings


Researchers have suggested that cyprinid fishes are less sensitive to chemical stress than comparable fish families, yet few empirically based evaluations of this hypothesis have been conducted. In this study, we developed a generalized linear mixed model in which the no-effect concentrations (NECs; threshold concentration below which no effect on survival is predicted during prolonged exposure) of 29 fish species from 13 families exposed to an acetylcholinesterase inhibitor pesticide (carbaryl, chlorpyrifos, or malathion) were used as the response variable. The corresponding specific somatic maintenance (SSM) rates, as a size-independent proxy for fish metabolism and a categorical variable regarding whether the species is a cyprinid, were used as the predictor variables. We included SSM rates in the analysis because previous work demonstrated that they are negatively correlated with NECs. Our results indicate that the NECs for cyprinid fishes were significantly higher than those for other fishes, suggesting that cyprinids are indeed less sensitive to the three studied pesticides. Although the SSM rates were negatively related with the NECs, the actual relationship between the two was not clear, implying that the importance of SSM rates may depend on the taxonomic group tested.


Species sensitivity Trait Tolerance Resistance Freshwater fish 



This study was supported by a Grant-in-Aid for Strategic Research Base Project for Private Universities funded by the Ministry of Education, Culture, Sport, Science, and Technology, Japan (2014–2018, No. S14111016), the Japan Science and Technology Agency's program to disseminate the Tenure Tracking System, and the Research Grant Program of Inamori Foundation. We thank multiple anonymous reviewers for providing helpful comments on previous versions of the manuscript.


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Copyright information

© The Japanese Society of Limnology 2017

Authors and Affiliations

  1. 1.Research Center for Life and Environmental SciencesToyo UniversityOuraJapan
  2. 2.Center of Mathematics for Social CreativityHokkaido UniversitySapporoJapan
  3. 3.Institute for Agro-Environmental SciencesNational Agriculture and Food Research OrganizationTsukubaJapan
  4. 4.Research Institute of Science for Safety and SustainabilityNational Institute of Advanced Industrial Science and TechnologyTsukubaJapan

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