The European Journal of Health Economics

, Volume 6, Issue 2, pp 124–130 | Cite as

Validating the EQ-5D with time trade off for the German population

  • W. GreinerEmail author
  • C. Claes
  • J. J. V. Busschbach
  • J.-M. Graf von der Schulenburg
Original papers


The aim of this survey study was to derive the societal values of the general public for the EuroQol EQ-5D. Using the same protocol as previously used in the United Kingdom, we compared the German values with the British. In face-to-face interviews a sample of 339 individuals in northern Germany valued 15 different health states from a sample of 36 states. Values were derived using the York MVH protocol for time trade-off (TTO) and a visual analogue scale (VAS). Values for all 243 health states of the EQ-5D were estimated by a regression model. The VAS values revealed close a resemblance to the British VAS results. German TTO values were higher than the British. This was especially the case for the worse health states. The results suggest that the TTO values are more related to national variables than values derived by VAS. The use of the TTO values of this investigation makes it possible to anticipate these cultural differences in studies carried out in Germany.


Cost-effectiveness Utility measurement Quality-adjusted life-years Quality of life Population study 



We thank Paul Dolan for his interest and advice in setting up this study.

Conflict of interest:

No information supplied.


  1. 1.
    Badia X et al (1999) Inconsistent responses in three preference-elicitation methods for health states. Soc Sci Med 49:943–50Google Scholar
  2. 2.
    Badia X et al (2001) A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states. Med Decis Making 21:7–16Google Scholar
  3. 3.
    Brazier JE (2002) The estimation a preference-based single index measure for health from the SF-36. J Health Econ 21:271–292CrossRefPubMedGoogle Scholar
  4. 4.
    Brooks R (1996) EuroQol: the current state of play. Health Policy 37:53–72CrossRefPubMedGoogle Scholar
  5. 5.
    Busschbach JJV et al (1997) Testing different parametric relations between the EuroQol health description and health valuation in students. In: Nord E (ed) Conference Proceedings of the EuroQol Plenary Meeting Oslo, 17–19 Oct 1996. National Institute of Public Health: OsloGoogle Scholar
  6. 6.
    Busschbach JJV et al (2003) A comparison of EQ-5D time tarde-off values obtained in Germany, the United Kingdom and Spain. In: Brooks R, Rabin R, de Charro F (eds) The measurement and valuation of health status using EQ-5D—a European perspective. Kluwer: Dordrecht, pp143–165Google Scholar
  7. 7.
    Dolan P (1997) Modeling valuations for EuroQol health states. Med Care 35:1095–1108CrossRefPubMedGoogle Scholar
  8. 8.
    Greiner W et al (2003) A European EQ-5D VAS valuation set. In: Brooks R, Rabin R, de Charro F (eds) The measurement and valuation of health status using EQ-5D—a European perspective. Kluwer: Dordrecht, pp 103–142Google Scholar
  9. 9.
    Macran S, Kind P (2000) Valuing the EQ-5D health states using a modified MVH protocol: preliminary results. In: Badia X, Herdman M, Roset M (eds) Stiges plenary meeting of the EuroQol Group 6–9 November 1999, Spain. Institut de Salut Publica de Catalunya: BarcelonaGoogle Scholar
  10. 10.
    Patrick DL, Starks HE, Cain KC, Uhlmann AF, Pearlman R (1994) Measuring preferences for health status worse than death. Med Decis Making 14:9–18Google Scholar
  11. 11.
    Torrance G (1986) Measurement of health state utilities for economic appraisal. J Health Econ 5:1–30Google Scholar
  12. 12.
    Tsuchiya A, Ikeda S, Ikegami N, Nishimura S, Sakai I, Fukuda T, Hamashima C, Hisashige A, Tamura M (2002) Estimating an EQ-5D population value set: the case of Japan. Health Econ 11:341–353Google Scholar

Copyright information

© Springer Medizin Verlag 2004

Authors and Affiliations

  • W. Greiner
    • 1
    • 3
    Email author
  • C. Claes
    • 1
  • J. J. V. Busschbach
    • 2
  • J.-M. Graf von der Schulenburg
    • 1
  1. 1.Center for Health Economics and Health System ResearchUniversity of HanoverGermany
  2. 2.Institute for Medical Psychology and PsychotherapyErasmus Medical CenterRotterdamThe Netherlands
  3. 3.Centre for Health Economics and Health System ResearchUniversity of HanoverHanoverGermany

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