The Journal of Headache and Pain

, Volume 5, Issue 2, pp 140–143 | Cite as

Report of cluster headache in a pair of monozygous twins

  • Pedro A. Kowacs
  • Elcio J. Piovesan
  • Lineu C. Werneck
  • Hudson Fameli
  • Marcos C. Lange
  • Salmo Raskin
BRIEF REPORT

Abstract

A pair of identical twins with cluster headache is described. Monozygosity was confirmed by the identification of 14 DNA markers. In spite of harboring the same genes, the clinical picture presented by the twins was not exactly the same. Cluster headache is probably the best known trigeminal-autonomic cephalalgia, but several questions regarding its pathophysiology remain to be answered. The cases described herein reinforce the role of genetic aspects in its etiology.

Key words

Cluster headache Genetic aspects Monozygous twins Trigeminal-autonomic cephalalgias Twins 

Copyright information

© Springer-Verlag Italia 2004

Authors and Affiliations

  • Pedro A. Kowacs
    • 1
  • Elcio J. Piovesan
    • 1
  • Lineu C. Werneck
    • 1
  • Hudson Fameli
    • 1
  • Marcos C. Lange
    • 1
  • Salmo Raskin
    • 2
  1. 1.Headache Section, Neurology Division, Internal Medicine DepartmentHospital de Clínicas da Universidade Federal do ParanáCuritibaBrazil
  2. 2.Laboratório GenétikaCuritibaBrazil

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