The Journal of Headache and Pain

, Volume 4, Issue 3, pp 168–170 | Cite as

Successful treatment of indomethacin-intolerant chronic paroxysmal hemicrania: report of two cases

  • Yusuf A. RajaballyEmail author


Chronic paroxysmal hemicrania (CPH) is a rare headache syndrome resulting in non-remitting, recurrent, intense, short-lasting pain, with typical, often total, responsiveness to indomethacin. Other drugs have anecdotally been reported to be potentially effective. Apparent unreponsiveness, in fact due to intolerance to this non-steroidal antiinflammatory drug, can lead to doubt about the initial diagnosis. Two such cases of CPH, for whom effective alternative treatment was eventually given, are described.

Key words

Chronic paroxysmal hemicrania Indomethacin Carbamazepine Verapamil Ketoprofen 

Copyright information

© Springer-Verlag Italia 2003

Authors and Affiliations

  1. 1.Department of NeurologyUniversity Hospitals of Leicester, Royal InfirmaryLeicesterUnited Kingdom

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