Clinical and Experimental Nephrology

, Volume 22, Issue 4, pp 977–978 | Cite as

Distinct renal outcomes for transcatheter aortic valve replacement and surgical repair

  • Abhilash KoratalaEmail author
  • Shahab Bozorgmehri
  • Amir Kazory
Letter to the editor

To the editor,

Aortic stenosis is one of the most common cardiac degenerative valvular diseases with an estimated prevalence of 1.3% in patients aged between 65 and 74 years and 2.8–4.6% in those aged 75 or more [1, 2]. Transcatheter aortic valve replacement (TAVR) has emerged as a viable option for the treatment of patients with aortic stenosis who are not suitable candidates for surgical aortic valve replacement (SAVR). Acute kidney injury (AKI) is considered an established postoperative complication that is associated with a significant increase in the risk of mortality [3]. We sought to explore the available evidence on the risk of AKI after TAVR as compared with SAVR.

We searched the articles cited in PubMed database from years 2000 to 2017 using key words “aortic stenosis” and “transcatheter aortic valve replacement”, and those evaluating the role of TAVR in management of aortic stenosis were reviewed. Randomized controlled trials (RCT) that contained data on comparative impact...


Compliance with ethical standards



Conflict of interest

The authors have declared that no conflict of interest exists.

Human and animal rights statement (with IRB Approval number)

This article does not contain any studies with human participants or animals performed by any of the authors. IRB approval is not applicable.


  1. 1.
    Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, et al. Burden of valvular heart diseases: a population-based study. Lancet. 2006;368(9540):1005–1011.CrossRefPubMedGoogle Scholar
  2. 2.
    Cheungpasitporn W, Thongprayoon C, Kashani K. Transcatheter aortic valve replacement: a kidney’s perspective. J Renal Inj Prev. 2016;5(1):1–7.CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Thongprayoon C, Cheungpasitporn W, Srivali N, Ungprasert P, et al. Acute kidney injury after transcatheter aortic valve replacement: a systematic review and meta-analysis. Am J Nephrol. 2015;41(4–5):372–382.CrossRefPubMedGoogle Scholar
  4. 4.
    Nielsen HH, Klaaborg KE, Nissen H, Terp K, et al. A prospective, randomised trial of transapical transcatheter aortic valve implantation vs. surgical aortic valve replacement in operable elderly patients with aortic stenosis: the STACCATO trial. EuroIntervention. 2012;8(3):383–389.CrossRefPubMedGoogle Scholar
  5. 5.
    Kodali SK, Williams MR, Smith CR, Svensson LG, et al. Two-year outcomes after transcatheter or surgical aortic-valve replacement. N Engl J Med. 2012;366(18):1686–1695.CrossRefPubMedGoogle Scholar
  6. 6.
    Adams DH, Popma JJ, Reardon MJ, Yakubov SJ, et al. Transcatheter aortic-valve replacement with a self-expanding prosthesis. N Engl J Med. 2014;370(19):1790–1798.CrossRefPubMedGoogle Scholar
  7. 7.
    Reardon MJ, Van Mieghem NM, Popma JJ, et al. Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients. N Engl J Med. 2017;376(14):1321–1331.CrossRefPubMedGoogle Scholar

Copyright information

© Japanese Society of Nephrology 2017

Authors and Affiliations

  1. 1.Division of Nephrology, Hypertension and Renal TransplantationUniversity of FloridaGainesvilleUSA

Personalised recommendations