Clinical and Experimental Nephrology

, Volume 21, Issue 3, pp 359–366 | Cite as

Renal Resistive Index: not only kidney

  • Pierpaolo Di NicolòEmail author
  • Antonio Granata
Review article


From growing data from the literature emerges that so-called ecoDoppler “Renal” Resistive Indexes (RRI) are not only specific markers of kidney damage and indicators of renal functional prognosis but they always express more clearly a strong link with the systemic circulation. In fact, some cardiovascular parameters such as aortic pulse pressure, aortic stiffness, abdominal aortic calcifications and clinical settings for instance heart failure progression have shown a great association with RRI. Relationships between renal and inflammatory indexes in hypertensive patients have been found and data from the literature on kidney transplants underline the capability of the graft RRI to change according to host hemodynamic features. The purpose of this article is to explain the emerging pathophysiological aspects of this relationship between renal microcirculation and cardiovascular system by emphasizing the importance for the ultrasonographer and for the nephrologist of not overlooking a global vision of the patient before interpreting the RRI.


Renal Doppler ultrasound Renal Resistive Index Cardiovascular system 


Compliance with ethical standards

Conflict of interest

The authors Pierpaolo Di Nicolò and Antonio Granata have declared that no conflict of interest exists.

Human and animal rights

This article does not contain any studies with human participants or animal performed by any of the authors.

Informed consent

Informed consent was obtained from all individual participants included in the article.


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Copyright information

© Japanese Society of Nephrology 2016

Authors and Affiliations

  1. 1.Nephrology and Dialysis Unit“S. Maria della Scaletta” HospitalImolaItaly
  2. 2.Nephrology and Dialysis Unit“St. Giovanni di Dio” HospitalAgrigentoItaly

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