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Journal of Clinical and Experimental Nephrology

, Volume 7, Issue 4, pp 296–300 | Cite as

Fibrillary glomerulonephritis associated with essential thrombocytosis

  • Kensuke Asaba
  • Akihiro Tojo
  • Maristela Lika Onozato
  • Natsuko Mimura
  • Makiko Kido
  • Atsuo Goto
  • Hisako Endo
  • Toshiro Fujita
CASE REPORT

Abstract

A 68-year-old man with a 30-year history of essential thrombocytosis developed nephrotic syndrome. Renal biopsy showed massive deposits of Congo red-negative periodic acid Schiff (PAS)-positive substance in the mesangium and capillary wall that was positive for IgG. Electron microscopic examination revealed 10- to 20-nm fibrils in the deposits, and there was no other organ involvement; thus, we diagnosed fibrillary glomerulonephritis. This is the first report of a case of fibrillary glomerulonephritis associated with essential thrombocytosis.

Key words

Fibrillary glomerulonephritis Essential thrombocytosis Nephrotic syndrome Myelofibrosis 

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Copyright information

© Springer-Verlag Tokyo 2003

Authors and Affiliations

  • Kensuke Asaba
    • 1
  • Akihiro Tojo
    • 1
  • Maristela Lika Onozato
    • 1
  • Natsuko Mimura
    • 1
  • Makiko Kido
    • 1
  • Atsuo Goto
    • 1
  • Hisako Endo
    • 2
  • Toshiro Fujita
    • 1
  1. 1.Division of Nephrology and EndocrinologyUniversity of TokyoTokyoJapan
  2. 2.Department of PathologyUniversity of TokyoTokyoJapan

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