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Effectiveness of topical use of Lietofix® in wound healing after pilonidalis sinus excision: a multicenter study by the Italian Society of Colorectal Surgery (SICCR)

  • SICCR PILONIDALIS STUDY GROUP
  • I. Giannini
  • R. Andreoli
  • F. P. Bianchi
  • V. Cavallaro
  • F. Corno
  • A. Geccherle
  • F. Ghiglione
  • A. Legnaro
  • L. Losacco
  • S. Marola
  • S. Orlandi
  • G. Pecorella
  • D. Pennisi
  • R. Perinotti
  • F. Poli
  • M. Pozzo
  • L. Pulzato
  • E. Schembari
  • S. Tafuri
  • G. Tegon
  • N. Tricomi
  • L. Velci
  • F. Vittadello
  • G. A. SantoroEmail author
Technical Advances
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Introduction

Pilonidal sinus disease (PSD) is a common inflammation of the sacrococcygeal region (26 pts/100.000 people), mostly affecting younger age and males (a male/female ratio 2:1) [1]. The disease can affect quality of life due to local pain or discomfort and be a significant cost to society due to absence from work before and even after therapy.

Open healing reduces the risk of recurrence by 35% when compared with any closed method [1]. However, open healing is associated with postoperative pain and discomfort and weeks of wound care. Its management is not standardized [2]. Wound dressings impregnated with antimicrobial agents (i.e. silver and alginates or gentamycin collagen sponge) and vacuum-assisted closure (VAC) have been used with controversial benefits. Topical application of hyaluronic acid derivatives and aloe vera have been proved effective in reducing postoperative pain and the burning sensation from surgical and chronic wounds and in accelerating the wound healing...

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The study was approved by the ethics committee of each center which participated in the trial.

Informed consent

All participants gave written informed consent.

References

  1. 1.
    Steele SR, Perry WB, Mills S, Buie WD (2013) Practice parameters for the management of pilonidal disease. Standards Practice Task Force of the American Society of Colon and Rectal Surgeons. Dis Colon Rectum 56:1021–1027CrossRefGoogle Scholar
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    Al-Khamis A, McCallum I, King PM, Bruce J (2010) Healing by primary versus secondary intention after surgical treatment for pilonidal sinus. Cochrane Database Syst Rev 20:CD006213Google Scholar
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    Segre D, Pozzo M, Perinotti R, Roche B (2015) The treatment of pilonidal disease: guidelines of the Italian Society of Colorectal Surgery (SICCR). Tech Coloproctol 19:607–613CrossRefGoogle Scholar
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    Sievert H, Evers T, Matevossian E, Hoenemann C, Hoffmann S, Doll D (2013) The influence of lifestyle (smoking and body mass index) on wound healing and long-term recurrence rate in 534 primary pilonidal sinus patients. Int J Colorectal Dis 28:1555–1562CrossRefGoogle Scholar
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    Stauffer VK, Luedi MM, Kauf P, Schmid M, Diekmann M, Wieferich K, Schnüriger B, Doll D (2018) Common surgical procedures in pilonidal sinus disease: a meta-analysis, merged data analysis, and comprehensive study on recurrence. Sci Rep 8:3058–3086CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • SICCR PILONIDALIS STUDY GROUP
  • I. Giannini
    • 1
  • R. Andreoli
    • 2
  • F. P. Bianchi
    • 3
  • V. Cavallaro
    • 4
  • F. Corno
    • 5
  • A. Geccherle
    • 2
  • F. Ghiglione
    • 5
  • A. Legnaro
    • 6
  • L. Losacco
    • 6
  • S. Marola
    • 5
  • S. Orlandi
    • 2
  • G. Pecorella
    • 4
  • D. Pennisi
    • 4
  • R. Perinotti
    • 7
  • F. Poli
    • 8
  • M. Pozzo
    • 7
  • L. Pulzato
    • 9
  • E. Schembari
    • 4
  • S. Tafuri
    • 3
  • G. Tegon
    • 9
  • N. Tricomi
    • 10
  • L. Velci
    • 10
  • F. Vittadello
    • 8
  • G. A. Santoro
    • 8
    Email author
  1. 1.UOC General SurgeryDi Venere HospitalBariItaly
  2. 2.Intestinal Diseases CentreDon Calabria HospitalNegrarItaly
  3. 3.Department of Biomedical Science and Human OncologyAldo Moro UniversityBariItaly
  4. 4.Colorectal UnitSurgical Clinic, Vittorio Emanuele UniversityCataniaItaly
  5. 5.SCDU General Surgery IUniversity of TurinTurinItaly
  6. 6.UO General SurgeryRovigo HospitalRovigoItaly
  7. 7.Department of General SurgeryDegli Infermi HospitalBiellaItaly
  8. 8.Pelvic Floor Unit, IV°Division of General SurgeryTreviso Regional HospitalTrevisoItaly
  9. 9.UCP San Camillo HospitalTrevisoItaly
  10. 10.UCP Casa di Cura CandelaPalermoItaly

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