Gastrointestinal stromal tumor with skeinoid fibers: an unusual presentation
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Gastrointestinal stromal tumors (GISTs) are a group of mesenchymal neoplasms originating from precursors of connective tissue cells of the gastrointestinal tract and typically occur in the elderly around the sixth decade of life . The most common sites of GISTs are the stomach (50–70%) and the small intestine (25–35%), whereas they are rarer in colon/rectum (5–10%), mesentery/omentum (7%), and esophagus (< 5%). GISTs originate within the bowel wall and can present with a wide clinical spectrum, thus their prognosis and treatment have not been clearly established, especially for GISTs of the colon.
Most GISTs (69%) are usually identified due to clinical signs and symptoms, such as gastrointestinal bleeding, abdominal pain and palpable abdominal mass. The diagnostic yield of endoscopy as a screening tool for GISTs is quite poor (33%) [2, 3].
Tumor size, mitotic rate, tumor location, kinase mutational status and occurrence of tumor rupture have been proposed to be predictors of...
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Conflict of interest
The authors declare that they have no conflict of interest.
Research involving human material has been performed in accordance with the Declaration of Helsinki of 1975, as revised in 2000 and 2008; the ethical standards of Good Clinical Practice; the applicable sections of the national medical device law; and the ethical code of the Università degli Studi della Campania “L. Vanvitelli” (approved with D.R. 992/2012).
Informed consent to participate in the study has been obtained from participant.
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