Techniques in Coloproctology

, Volume 15, Issue 4, pp 371–375 | Cite as

Beyond hematoxylin and eosin: the importance of immunohistochemical techniques for evaluating surgically resected constipated patients

  • G. BassottiEmail author
  • V. Villanacci
  • B. Salerni
  • C. A. Maurer
  • G. Cathomas


Chronic constipation requiring surgical ablation for intractability is often a frustrating condition from the pathologist’s point of view. In fact, limiting the histological examination to only hematoxylin–eosin staining usually yields only the information that there are no abnormalities. By employing some simple and widely available immunohistochemical methods, discussed in this review, it is possible to gather data that may help in explaining the pathophysiological basis of constipation in these patients.


Constipation Histology Immunohistochemistry Surgery 


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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • G. Bassotti
    • 1
    • 6
    Email author
  • V. Villanacci
    • 2
  • B. Salerni
    • 3
  • C. A. Maurer
    • 4
  • G. Cathomas
    • 5
  1. 1.Gastroenterology and Hepatology Section, Department of Clinical and Experimental MedicineUniversity of PerugiaPerugiaItaly
  2. 2.Second Pathology Section, Department of Laboratory DiagnosticsUniversity of BresciaBresciaItaly
  3. 3.2nd Surgical Chair, Department of Surgery, Spedali CiviliUniversity of BresciaBresciaItaly
  4. 4.Department of SurgeryLiestal HospitalLiestalSwitzerland
  5. 5.Cantonal Institute of PathologyLiestal HospitalLiestalSwitzerland
  6. 6.Clinica di Gastroenterologia ed EpatologiaOspedale Santa Maria della MisericordiaSan Sisto, PerugiaItaly

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