Techniques in Coloproctology

, Volume 14, Issue 2, pp 181–184 | Cite as

Synchronous collision malignant melanoma and adenocarcinoma of the rectum

  • A. R. Dias
  • R. A. Pinto
  • E. Mory
  • I. C. Silva
  • S. A. C. Siqueira
  • S. C. Nahas
  • I. Cecconello
  • S. D. Wexner
Case Report


“Collision tumors” consist of two independent but coexisting tumors. This uncommon situation might be easily mistaken for a composite tumor where one histogenetic event originates from two apparently distinct neoplasms. Colorectal collisions are particularly unusual; here, we report the exceedingly rare case of a 61-year-old man with malignant melanoma and adenocarcinoma colliding in the rectum. Collision tumors have an idiopathic pathophysiology and in fact “accidental meeting” is accepted by many authors. This article discusses the concepts about cancer development, which are overlooked by this hypothesis, another theory to explain that this rare occurrence involves microenvironment changes.


Collision tumor Melanoma Adenocarcinoma Physiopathology 


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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • A. R. Dias
    • 1
  • R. A. Pinto
    • 1
    • 3
  • E. Mory
    • 1
  • I. C. Silva
    • 2
  • S. A. C. Siqueira
    • 2
  • S. C. Nahas
    • 1
  • I. Cecconello
    • 1
  • S. D. Wexner
    • 3
  1. 1.Department of Gastroenterology, Division of Colorectal Surgery, Hospital das ClinicasUniversity of Sao Paulo, School of MedicineSao PauloBrazil
  2. 2.Department of Pathology, Hospital das ClinicasUniversity of Sao Paulo, School of MedicineSao PauloBrazil
  3. 3.Department of Colorectal SurgeryCleveland Clinic FloridaWestonUSA

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