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Techniques in Coloproctology

, Volume 7, Issue 2, pp 82–84 | Cite as

Effects of the use of fibrin glue around the colonic anastomosis of the rat

  • I. Kanellos
  • I. Mantzoros
  • I. Goulimaris
  • E. Zacharakis
  • A. Zavitsanakis
  • D. Betsis
ORIGINAL ARTICLE

Abstract.

Background:

This study was aimed at examining whether the addition of fibrin glue to a sutured colonic anastomosis improves its healing or not.

Methods:

We studied the effect of adding fibrin glue on a sutured colonic anastomosis. Thirty-six Wistar rats were randomized into two groups of 18 rats each. A sutured anastomosis was performed in all rats. Fibrin glue was applied around the anastomosis of the rats of group B. Rats were sacrificed on the eighth postoperative day.

Results:

The rate of anastomotic leakage was found not to be significantly different between the two groups. The mean bursting pressure of the colonic anastomoses was significantly higher in group B (fibrin-treated) than in group A.

Conclusion:

Fibrin glue application around a sutured anastomosis provides a safer anastomosis which is stronger than the sutured one.

Key words

Colonic anastomosis Fibrin glue Healing 

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Copyright information

© Springer-Verlag Italia 2003

Authors and Affiliations

  • I. Kanellos
    • 1
  • I. Mantzoros
    • 1
  • I. Goulimaris
    • 1
  • E. Zacharakis
    • 1
  • A. Zavitsanakis
    • 1
  • D. Betsis
    • 1
  1. 1.Fourth Department of SurgeryAristotle University of ThessalonikiGreece

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