International Journal of Clinical Oncology

, Volume 17, Issue 2, pp 185–188 | Cite as

Synchronous and metachronous ureteric metastases from adenocarcinoma of the colon

  • Maitrey Darrad
  • Samuel Harper
  • Anju Verghese
  • John Leveckis
  • Sanjeev Pathak
Case Report
  • 133 Downloads

Abstract

Primary adenocarcinoma of the ureter occurs in only <1%. Furthermore, metastatic carcinoma to the ureter is very rare and has been described to occur from breast, lung, stomach and prostate cancers. However, metastases to the ureter from colon cancers are extremely rare, and have been largely reported as incidental post-mortem cases. We describe two cases of asymptomatic ureteric metastases secondary to adenocarcinoma of the colon; one is synchronous, whilst the other is a metachronous ureteric metastasis. With the increasing use of radiological imaging modalities such as CT and MRI (Clin Imaging 2001;25:197–202, 2001), together with increasing survival rates of primary cancers, asymptomatic ureteric metastases are more likely to be diagnosed. In summary, metastatic ureteric carcinoma of colonic origin must be considered as a differential diagnosis when there is a radiological abnormality of the ureter in patients with a history of adenocarcinoma of the colon. This should be considered even in patients with colon adenocarcinoma who have previously undergone adjuvant chemotherapy with curative intent.

Keywords

Metastases Ureter Urothelial cancer Colon adenocarinoma 

Notes

Conflict of interest

No author has any conflict of interest.

References

  1. 1.
    Atasoy C, Yagci C, Fitoz S et al (2001) Cross-sectional imaging in ureter tumors: findings and staging accuracy of various modalities. Clin Imaging 25:197–202PubMedCrossRefGoogle Scholar
  2. 2.
    Hobdy EM, Ciesielski TE, Kummar S (2003) Unusual sites of colorectal cancer metastasis. Clin Colorectal Cancer 3:54–57PubMedCrossRefGoogle Scholar
  3. 3.
    Chang YH, Chuang CK, Ng KF et al (2007) Urethral metastasis from a colon carcinoma. Urology 69:575.e1–3Google Scholar
  4. 4.
    Dickson BC, Fornasier VL, Streutker CJ et al (2007) Ureteric obstruction: an unusual presentation of metastatic colon carcinoma. Can J Urol 14:3526–3528PubMedGoogle Scholar
  5. 5.
    Thorup B, Fabrin K, Lund L (2001) Implantation metastasis in ureter from a colonic adenocarcinoma. Scand J Urol Nephrol 35:420–421PubMedCrossRefGoogle Scholar
  6. 6.
    Anderstrom C, Johansson SL, Pettersson S et al (1989) Carcinoma of the ureter: a clinicopathologic study of 49 cases. J Urol 142:280–283PubMedGoogle Scholar
  7. 7.
    Spires SE, Banks ER, Cibull ML et al (1993) Adenocarcinoma of renal pelvis. Arch Pathol Lab Med 117:1156–1160PubMedGoogle Scholar
  8. 8.
    Fitch WP, Robinson JR, Radwin HW (1976) Metastatic carcinoma of the ureter. Arch Surg 111:874–876PubMedCrossRefGoogle Scholar
  9. 9.
    Stearns DB, Gordon SK (1960) Ureteral metastasis secondary to carcinoma of the large bowel. Am J Surg 99:244–246PubMedCrossRefGoogle Scholar
  10. 10.
    Marincek B, Scheidegger JR, Studer UE et al (1993) Metastatic disease of the ureter: patterns of tumoral spread and radiologic findings. Abdom Imaging 18:88–94PubMedCrossRefGoogle Scholar
  11. 11.
    Kuo SM, Lin CM, Cha TL et al (2009) Metastatic ureteral tumour from adenocarcinoma of colon. J Med Sci 120:139–141Google Scholar
  12. 12.
    Winalski CS, Lipman JC, Tumeh SS (1990) Ureteral neoplasms. Radiographics 10:271–283PubMedGoogle Scholar
  13. 13.
    Kummar S, Fogarasi M, Canova A et al (2002) Cytokeratin 7 and 20 staining for the diagnosis of lung and colorectal adenocarcinoma. Br J Cancer 86:1884–1887PubMedCrossRefGoogle Scholar
  14. 14.
    Wang HL, Lu DW, Yerian LM et al (2001) Immunohistochemical distinction between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma. Am J Surg Pathol 25:1380–1387PubMedCrossRefGoogle Scholar

Copyright information

© Japan Society of Clinical Oncology 2011

Authors and Affiliations

  • Maitrey Darrad
    • 1
  • Samuel Harper
    • 1
  • Anju Verghese
    • 2
  • John Leveckis
    • 1
  • Sanjeev Pathak
    • 1
  1. 1.Department of UrologyDoncaster Royal InfirmaryDoncasterUK
  2. 2.Department of PathologyDoncaster Royal InfirmaryDoncasterUK

Personalised recommendations