International Journal of Clinical Oncology

, Volume 12, Issue 5, pp 356–362

Evaluation of mass-like consolidation after stereotactic body radiation therapy for lung tumors

  • Yukinori Matsuo
  • Yasushi Nagata
  • Takashi Mizowaki
  • Kenji Takayama
  • Takashi Sakamoto
  • Masato Sakamoto
  • Yoshiki Norihisa
  • Masahiro Hiraoka



The purpose of this study was to evaluate the characteristics of mass-like consolidation of the lung on computed tomography (CT) after stereotactic body radiation therapy (SBRT) retrospectively.


Forty lung tumors in 37 patients who underwent SBRT were evaluated. Mass-like consolidation was defined as a dense consolidation that newly appeared over or around the original tumor, which included radiation-induced lung injury (RILI) and local recurrence. Time of appearance, initial CT findings (ectatic bronchi and conformity to dose distribution) and serial changes in the size of the mass-like consolidation were evaluated.


Mass-like consolidation appeared in 27 (68%) of 40 tumors at a median of 5 months after SBRT. Follow-up examination revealed that 24 (89%) of the 27 mass-like consolidations were RILI and 3 (11%) were local recurrence. There were no significant differences in the initial CT findings between RILI and local recurrence. The size of the mass-like consolidation varied in the 12 months after SBRT. After 12 months or more, however, the size did not increase in any of the RILI cases, but it did increase in all recurrence cases.


Mass-like consolidations were observed in 68% of cases at a median of 5 months after SBRT. Although most of the mass-like consolidations were RILI, local recurrence was observed in a few cases. Early detection of local recurrence after SBRT was difficult.

Key words

Radiation-induced lung injury Local recurrence Stereotactic body radiation therapy Lung tumor 


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Copyright information

© The Japan Society of Clinical Oncology 2007

Authors and Affiliations

  • Yukinori Matsuo
    • 1
  • Yasushi Nagata
    • 1
  • Takashi Mizowaki
    • 1
  • Kenji Takayama
    • 1
  • Takashi Sakamoto
    • 1
    • 2
  • Masato Sakamoto
    • 3
  • Yoshiki Norihisa
    • 1
  • Masahiro Hiraoka
    • 1
  1. 1.Department of Radiation Oncology and Image-Applied Therapy, Graduate School of MedicineKyoto UniversityKyotoJapan
  2. 2.Department of Radiation Oncology, Graduate School of Medical SciencesKumamoto UniversityKumamotoJapan
  3. 3.Department of RadiologyJapanese Red Cross Society Wakayama Medical CenterWakayamaJapan

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