International Journal of Clinical Oncology

, Volume 11, Issue 5, pp 344–350

Function-preserving surgery for breast cancer

  • Hideo Inaji
  • Chiyomi Egawa
  • Yoshifumi Komoike
  • Kazuyoshi Motomura
  • Kinji Nishiyama
  • Tatsuki R. Kataoka
  • Hiroki Koyama


Breast-conserving treatment is well established as a safe method of treatment for the majority of breast cancers. Issues to be addressed concerning breast-conserving treatment include the omission of radiation therapy in low-risk patients, optimal local and systemic treatment for ipsilateral breast tumor recurrence, classification of ipsilateral breast tumor recurrence into true recurrences and new primary cancers, and the selection of patients who are eligible for breast conservation after neoadjuvant chemotherapy. There is much evidence that sentinel node biopsy is an accurate method of screening for axillary nodal status in patients with early breast cancer. Clearly, the avoidance of axillary dissection improves quality of life. The feasibility, accuracy, and timing of sentinel node biopsy in patients undergoing neoadjuvant chemotherapy are not yet clear. Also, the clinical significance of micrometastasis should be evaluated to determine the optimal application of sentinel node biopsy. There is interest in replacing breast-conserving treatment by nonsurgical ablation, although additional findings are needed to show that this technique is a true advance in breast cancer treatment.

Key words

Breast cancer Breast-conserving treatment Ipsilateral breast tumor recurrence Sentinel node biopsy Nonsurgical ablation 


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Copyright information

© The Japan Society of Clinical Oncology 2006

Authors and Affiliations

  • Hideo Inaji
    • 1
  • Chiyomi Egawa
    • 1
  • Yoshifumi Komoike
    • 1
  • Kazuyoshi Motomura
    • 1
  • Kinji Nishiyama
    • 2
  • Tatsuki R. Kataoka
    • 3
  • Hiroki Koyama
    • 1
  1. 1.Department of Breast SurgeryOsaka Medical Center for Cancer and Cardiovascular Diseases, Osaka Prefectural Hospital OrganizationOsakaJapan
  2. 2.Department of Radiation OncologyOsaka Medical Center for Cancer and Cardiovascular Diseases, Osaka Prefectural Hospital OrganizationOsakaJapan
  3. 3.Department of PathologyOsaka Medical Center for Cancer and Cardiovascular Diseases, Osaka Prefectural Hospital OrganizationOsakaJapan

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