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Demographic and morphological characteristics associated with rupture status of anterior communicating artery aneurysms

  • Xiangke MaEmail author
  • Yang Yang
  • Dongtao Liu
  • Yiming Zhou
  • Weihua Jia
Original Article
  • 9 Downloads

Abstract

The aim of this study is to characterize demographic and morphologic characteristics of aneurysms located in the anterior communicating artery (ACoA) and to investigate possible associations between these characteristics and aneurysm rupture. We investigated 112 consecutive patients (72 ruptured and 40 unruptured) with ACoA aneurysms from a single-center database. The effects of demographic and morphologic characteristics on the risk of rupture in ACoA aneurysms were tested using univariate and multivariate logistic regression analyses, respectively. We found that larger size, greater size ratio, larger flow angle, irregular shape, and smoking of the patient were associated with the rupture of ACoA aneurysms based on univariate analysis. Size ratio (OR = 3.890, P = 0.003), irregular shape (OR = 1.068, P = 0.001), flow angle (OR = 1.054, P = 0.001), and current smoking (OR = 4.435, P = 0.009) were the strongest factors related to ruptured ACoA aneurysms based on multivariate logistic regression analysis. The areas under the curves for the flow angle and size ratio were 0.742 (95% CI 0.646–0.838; P = 0.001) and 0.736 (95% CI 0.621–0.796; P = 0.001), respectively. The strongest risk factors for rupture include size ratio, irregular shape, flow angle, and current smoking. These features should be taken into consideration to aid in the prediction of the rupture risk of ACoA aneurysms.

Keywords

Anterior communicating artery aneurysms Intracranial aneurysm rupture Rupture Subarachnoid hemorrhage 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Approval for the retrospective study was obtained from the research ethics committee of Chaoyang Hospital affiliated with the Capital Medical University.

Informed consent

All individual participants included in the study provided informed consent.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Neurosurgery, Beijing Chaoyang HospitalCapital Medical UniversityBeijingChina
  2. 2.Department of NeurosurgeryUniversity Hospital of ZurichZurichSwitzerland
  3. 3.Department of Neuroradiology, Beijing Chaoyang HospitalCapital Medical UniversityBeijingChina

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