Olfactory function in patients after transsphenoidal surgery for pituitary adenomas—a short review
- 263 Downloads
Olfaction is an important sensory input that obviously affects many daily activities. However, olfactory dysfunction (hyposmia and anosmia) leads to a pronounced decrease in quality of life. Surprisingly, little attention has been paid to olfactory changes after transsphenoidal surgery for pituitary tumors. In this review, we summarize current knowledge of the effects of transsphenoidal pituitary surgery on olfaction and compare different surgical techniques. Based on selected studies, the endoscopic approach, in comparison with the microscopic approach, seems to be superior in terms of preservation of olfactory function, although the quality of data from these studies is generally poor. The best results were observed when the endoscopic approach was used without harvesting of the nasoseptal flap.
KeywordsOlfaction Pituitary adenoma Transsphenoidal approach Endoscopic surgery Microscopic surgery Skull base
This study is supported by 15-327 91A, MO 1012, Q25.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
Ethical approval is not needed for this type of review.
Informed consent is not needed for this type of review.
- 2.Alobid I, Enseñat J, Mariño-Sánchez F, de Notaris M, Centellas S, Mullol J, Bernal-Sprekelsen M (2013) Impairment of olfaction and mucociliary clearance after expanded endonasal approach using vascularized septal flap reconstruction for skull base tumors. Neurosurgery 72(4):540–546CrossRefPubMedGoogle Scholar
- 7.Escada P (2013) Localization and distribution of human olfactory mucosa in the nasal cavities. Acta Medica Port 26(3):200–207Google Scholar
- 21.Kim DH, Hong Y-K, Jeun S-S, Park YJ, Kim SW, Cho JH, Kim BY, Han S, Lee YJ, Hwang JH, Kim SW (2016) Intranasal volume changes caused by the endoscopic endonasal transsphenoidal approach and their effects on nasal functions. PLoS One. https://doi.org/10.1371/journal.pone.0151531