Teflon granuloma after microvascular decompression for hemifacial spasm: a case report and literature review


Teflon has been commonly used as a surgical material. In particular, Teflon has been considered suitable for microvascular decompression of cranial nerves, as it is a stable, inert substance that does not resorb or migrate. Giant cell foreign body reactions after microvascular decompression (MVD) have been reported, but this rare complication has not been well recognized. Here, we report one case of Teflon granuloma that occurred 4 years after MVD for hemifacial spasm. We discuss the cause, histopathological analysis, particular MVD surgical methods, and management of Teflon granuloma.

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I would like to thank Hiroyuki Enomoto M.D. for useful discussions. I am grateful for assistance with the numerical simulations and carefully proofreading this manuscript from him.

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Correspondence to Kazunori Oda.

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This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

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The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from 61-year-old male with recurrent left-sided facial paralysis, progressive hearing loss and fever as the case presented.

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Oda, K., Higuchi, T., Murai, Y. et al. Teflon granuloma after microvascular decompression for hemifacial spasm: a case report and literature review. Neurosurg Rev 40, 513–516 (2017) doi:10.1007/s10143-017-0865-5

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  • Microvascular decompression
  • Teflon granuloma
  • Hemifacial spasm
  • Mononuclear cells