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House dust microbiome and human health risks

  • Yifan Shan
  • Weidong WuEmail author
  • Wei Fan
  • Tari Haahtela
  • Guicheng Zhang
Review

Abstract

People spend a lot of time indoors and the indoor microbiome is a major part of the environment that we are exposed to. However, awareness of the exposure to the indoor microbiome and its health effects remains poor. Outdoor environment (soil and air), indoor sources (ventilation, dampness and building materials), human occupants, and pets compose the indoor microbial community. It has been estimated that up to 500–1000 different species can be present in house dust. House dust is a major source and reservoir of indoor microbiome, which influences human microbiome and determines health and disease. Herein, we review the origins and the components of the fungal and bacterial communities in house dust and their possible effect on human health, in particular on allergic disorders, intestinal microbiome, and immune responses. We expect to lay a solid foundation for the further study on the mechanisms of how the house dust microbes interact with the host microbiome and the human immune system.

Keywords

House dust microbiome Fungal community Bacterial community Allergic diseases Gut microbiome 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Yifan Shan
    • 1
  • Weidong Wu
    • 1
    Email author
  • Wei Fan
    • 1
  • Tari Haahtela
    • 2
  • Guicheng Zhang
    • 3
  1. 1.School of Public HealthXinxiang Medical UniversityXinxiangPeople’s Republic of China
  2. 2.Skin and Allergy HospitalHelsinki University Central HospitalHelsinkiFinland
  3. 3.School of Public HealthCurtin UniversityPerthAustralia

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